ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2015
Prevalence of Whipple's disease in north-western Italy.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 71 citations in OpenAlex.
- Whipple Disease: A Two-Decade Multisystem Masquerade Preceding Gastrointestinal Presentation.ACG case reports journal · 2026Article
- Whipple's endocarditis and biologic response modifiers: a case-based review of an intricate host-pathogen interaction.Infection · 2026Review
- Prevalence, characteristics, and clinical outcomes of Whipple disease in patients initially diagnosed with a rheumatic disease: a large nested case-control study in the Eastern Netherlands.EULAR rheumatology open · 2026Article
- Rare but Critical: SevereClinical case reports · 2026Article
- Unraveling the Mystery: A Report of a Rare Case of Whipple's Disease Diagnosed After Months of Unexplained Symptoms.Cureus · 2025Article
- Clinical Features of Patients withInfection and drug resistance · 2025Article
- Successful Management of Whipple's Disease in a 46-Year-Old British Woman: A Case Report.Cureus · 2025Article
- Whipple Disease With Central Nervous System Involvement.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024Article
- Whipple's disease of the respiratory system: A case report.Experimental and therapeutic medicine · 2024Article
- Whipple Disease Presenting as Isolated Transverse Myelitis with Permanent Neurological Damage in a Patient with Systemic Lupus Erythematosus: A Case Report of a Difficult Diagnosis with a Literature Review.Infectious disease reports · 2024Article
- Clinical, Laboratory, and Imaging Characteristics of Tropheryma Whipplei Detection in Bronchoalveolar Lavage Fluid Using Next-Generation Sequencing: A Case-Control Study.Infection and drug resistance · 2024Article
- Use of bevacizumab in a patient with Whipple's disease: managing diagnostic uncertainty.BMJ case reports · 2023Article
- Whipple's Disease; An Overlooked Diagnosis.Middle East journal of digestive diseases · 2023Article
- Current knowledge of the immune reconstitution inflammatory syndrome in Whipple disease: a review.Frontiers in immunology · 2023Review
- Whipple's disease review, prevalence, mortality, and characteristics in the United States: A cross-sectional national inpatient study.Medicine · 2022Article
- Challenging case of Whipple's disease: The contribution of radiology.Radiology case reports · 2022Article
- Enteropathies with villous atrophy but negative coeliac serology in adults: current issues.BMJ open gastroenterology · 2021Review
- Whipple's disease? A case report and discussion.Medicine and pharmacy reports · 2021Article
- Whipple's disease: the great masquerader-a high level of suspicion is the key to diagnosis.BMC gastroenterology · 2021Article
- Severe Pneumonia Caused by Infection WithFrontiers in public health · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whipple's disease (WD) is a rare systemic infection due, in genetically susceptible individuals, to Tropheryma whipplei, a heterogeneous Gram-positive actinobacteria. Although it has already been recognised that WD affects mainly middle-aged Caucasian men, the prevalence of WD is virtually unknown. The annual incidence of WD in the general population is said to be less than 1 per 1,000,000, but scientific evidence for these figures is still lacking. On the basis of the number of patients recorded with a diagnosis of Whipple's disease in the regional registers for rare diseases of Lombardia, Liguria and Piemonte-Valle d'Aosta regions, we studied the prevalence of WD in the north-western part of Italy. Forty-six patients with Whipple's disease were recorded in these regions (13 females; mean age at diagnosis 52.1 ± 11.1 years). Since 16,130,725 inhabitants live in these four regions, prevalence of WD in the general population is 3/10(6) and almost 30% of the patients are females. WD is certainly a rare disease but it also affects women in a considerable proportion of cases.
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