Evidence map›Paper›PMID 25803511›Full record

ArticlePhysics in medicine and biology2015

Motionless electromagnetic phase stepping versus mechanical phase stepping in x-ray phase-contrast imaging with a compact source.

Katherine J Harmon, Houxun Miao, Andrew A Gomella, Eric E Bennett, Barbara A Foster, Priya Bhandarkar, Han Wen

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katherine J HarmonImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Houxun MiaoImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Andrew A GomellaImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Eric E BennettImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Barbara A FosterBreast Imaging Center, Walter Reed National Military Medical Center, Bethesda, MD 20889, USA.
Priya BhandarkarBreast Imaging Center, Walter Reed National Military Medical Center, Bethesda, MD 20889, USA.
Han WenImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Funding

NHLBI Animal Program DivisionZIGHL006020 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CLARK, TANNIA · 2009 to 2025
$47.3M
X-Ray Phase Contrast Imaging Concepts and SystemsZIAHL004606 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI WEN, HAN · 2009 to 2022
$10.1M
TECHNOLOGICAL DEVELOPMENT OF HIGH FIELD MAGNETIC RESONANCE IMAGINGZ01HL004606 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI WEN, HAN · 1997 to 2008
$4.3M
Intramural NIH HHS Z01 HL004606
6 · The paper itself

Abstract

X-ray phase contrast imaging based on grating interferometers detects the refractive index distribution of an object without relying on radiation attenuation, thereby having the potential for reduced radiation absorption. These techniques belong to the broader category of optical wavefront measurement, which requires stepping the phase of the interference pattern to obtain a pixel-wise map of the phase distortion of the wavefront. While phase stepping traditionally involves mechanical scanning of a grating or mirror, we developed electromagnetic phase stepping (EPS) for imaging with compact sources to obviate the need for mechanical movement. In EPS a solenoid coil is placed outside the x-ray tube to shift its focal spot with a magnetic field, causing a relative movement between the projection of the sample and the interference pattern in the image. Here we present two embodiments of this method. We verified experimentally that electromagnetic and mechanical phase stepping give the same results and attain the same signal-to-noise ratios under the same radiation dose. We found that the relative changes of interference fringe visibility were within 3.0% when the x-ray focal spot was shifted by up to 1.0 mm in either direction. We conclude that when using x-ray tube sources, EPS is an effective means of phase stepping without the need for mechanical movement.

Indexed as

Electromagnetic PhenomenaMicroscopy, Phase-ContrastMotionRadiographySignal-To-Noise RatioX-Rays

Identifiers

PMID25803511
PMCPMC6933752

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.