Evidence map›Paper›PMID 25803399›Full record

ArticleThe American journal of gastroenterology2015

Emergency department burden of constipation in the United States from 2006 to 2011.

Thomas Sommers, Caroline Corban, Neil Sengupta, Michael Jones, Vivian Cheng, Andrea Bollom, Samuel Nurko, John Kelley, Anthony Lembo

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in The American journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 43 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03335969 nawithdrawnnot on this mapstarted 2018, after this paper: background citation

Evaluation of the HyGIeaCare Procedure for Patients With Chronic Constipation

TypeinterventionalSponsorHyGIeaCare, Inc.Ran2018 to 2019Enrolled0ConditionsConstipation - FunctionalArmscolon irrigation
NCT03458390 nacompletednot on this mapstarted 2019, after this paper: background citation

Colon Irrigation Using HyGIeaCare as Prep for PillCam COLON Procedure

TypeinterventionalSponsorHyGIeaCare, Inc.Ran2019 to 2020Enrolled10ConditionsScreening ColonoscopyArmsHyGIeaCare colon irrigation
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Traditional, complementary and alternative medicine in children constipation: a systematic review.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2019
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Article
  9. Article
  10. Clinical Features, CT Imaging Decisions and Yield by Age in Adults With Abdominal Pain in the Emergency Department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Association between constipation and the development of asthma: a meta-analysis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2022
    Article
  17. Article
  18. Article
  19. Status of Constipation and Its Association with Sarcopenia in Older Adults: A Population-Based Cohort Study.International journal of environmental research and public health · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thomas SommersDivision of Gastroenterology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
Caroline CorbanDivision of Gastroenterology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
Neil SenguptaDivision of Gastroenterology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
Michael JonesMacquarie University, Sydney, New South Wales, Australia.
Vivian ChengDivision of Gastroenterology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
Andrea BollomDivision of Gastroenterology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
Samuel NurkoDivision of Gastroenterology, Children's Hospital, Boston, Massachusetts, USA.
John KelleyPsychology Department, Endicott College, Beverly, Massachusetts, USA.
Anthony LemboDivision of Gastroenterology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAlthough constipation is typically managed in an outpatient setting, there is an increasing trend in the frequency of constipation-related hospital visits. The aim of this study was to analyze trends related to chronic constipation (CC) in the United States with respect to emergency department (ED) visits, patient and hospital characteristics, and associated costs.

methodsData from 2006 to 2011, in which constipation (The International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) diagnosis codes 564.00-564.09) was the primary discharge diagnosis, were obtained from the National Emergency Department Sample (NEDS).

resultsBetween 2006 and 2011, the frequency of constipation-related ED visits increased by 41.5%, from 497,034 visits to 703,391 visits, whereas the mean cost per patient rose by 56.4%, from $1,474 in 2006 to $2,306 in 2011. The aggregate national cost of constipation-related ED visits increased by 121.4%, from $732,886,977 in 2006 to $1,622,624,341 in 2011. All cost data were adjusted for inflation and reported in 2014 dollars. Infants (<1 year old) had the highest rate of constipation-related ED visits in both 2006 and 2011. The late elders (85+ years) had the second highest constipation-related ED visit rate in 2006; however, the 1- to 17-year-old age group experienced a 50.7% increase in constipation-related ED visit rate from 2006 to 2011 and had the second highest constipation-related ED visit rate in 2011.

conclusionsThe frequency of and the associated costs of ED visits for constipation are significant and have increased notably from 2006 to 2011.

Indexed as

Cost of IllnessHospital CostsAdolescentAdultAgedAged, 80 and overAge FactorsChildChild, PreschoolComorbidityConfounding Factors, EpidemiologicConstipationEmergency Service, HospitalFemaleHumansInfant

Identifiers

PMID25803399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.