ArticlePLoS neglected tropical diseases2015
What drives the occurrence of the melioidosis bacterium Burkholderia pseudomallei in domestic gardens?
Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 45 citations in OpenAlex.
- Dry Season Melioidosis in the Tropical North of Australia.Pathogens (Basel, Switzerland) · 2026Article
- Interaction effects of physicochemical factors on the growth of Burkholderia pseudomallei in soil microcosms.PLoS neglected tropical diseases · 2026Article
- Rainfall-Driven Mobilisation of Clinically RelevantPathogens (Basel, Switzerland) · 2026Article
- Missing links of melioidosis in India: a cross-sectional analysis of case reports, agrometeorological and socioeconomic factors.Scientific reports · 2025Article
- Melioidosis in goats at a single Australian farm was caused by multiple diverse lineages of Burkholderia pseudomallei present in soil.PLoS neglected tropical diseases · 2024Article
- Burkholderia pseudomallei and melioidosis.Nature reviews. Microbiology · 2024Review
- Clinical Manifestations and Genomic Evaluation of Melioidosis Outbreak among Children after Sporting Event, Australia.Emerging infectious diseases · 2023Review
- Expanding the Geographic Boundaries of Melioidosis in Queensland, Australia.The American journal of tropical medicine and hygiene · 2023Article
- Distribution of Burkholderia pseudomallei within a 300-cm deep soil profile: implications for environmental sampling.Scientific reports · 2022Article
- Co-evolutionary Signals Identify Burkholderia pseudomallei Survival Strategies in a Hostile Environment.Molecular biology and evolution · 2022Article
- The NarX-NarL two-component system regulates biofilm formation, natural product biosynthesis, and host-associated survival in Burkholderia pseudomallei.Scientific reports · 2022Article
- Increased Incidence of Melioidosis in Far North Queensland, Queensland, Australia, 1998-2019.Emerging infectious diseases · 2021Article
- RegAB Homolog of Burkholderia pseudomallei is the Master Regulator of Redox Control and involved in Virulence.PLoS pathogens · 2021Article
- Human Melioidosis.Clinical microbiology reviews · 2020Review
- Erythritol as a single carbon source improves cultural isolation of Burkholderia pseudomallei from rice paddy soils.PLoS neglected tropical diseases · 2019Article
- Opportunistic pathogens and large microbial diversity detected in source-to-distribution drinking water of three remote communities in Northern Australia.PLoS neglected tropical diseases · 2019Article
- Burkholderia pseudomallei, the causative agent of melioidosis, is rare but ecologically established and widely dispersed in the environment in Puerto Rico.PLoS neglected tropical diseases · 2019Article
- Implications of environmental and pathogen-specific determinants on clinical presentations and disease outcome in melioidosis patients.PLoS neglected tropical diseases · 2019Article
- Melioidosis in the Torres Strait Islands, Australia: Exquisite Interplay between Pathogen, Host, and Environment.The American journal of tropical medicine and hygiene · 2019Article
- Presence ofTropical medicine and infectious disease · 2019Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melioidosis is an often fatal infectious disease affecting humans and animals in tropical regions and is caused by the saprophytic environmental bacterium Burkholderia pseudomallei. Domestic gardens are not only a common source of exposure to soil and thus to B. pseudomallei, but they also have been found to contain more B. pseudomallei than other environments. In this study we addressed whether anthropogenic manipulations common to gardens such as irrigation or fertilizers change the occurrence of B. pseudomallei. We conducted a soil microcosm experiment with a range of fertilizers and soil types as well as a longitudinal interventional study over three years on an experimental fertilized field site in an area naturally positive for B. pseudomallei. Irrigation was the only consistent treatment to increase B. pseudomallei occurrence over time. The effects of fertilizers upon these bacteria depended on soil texture, physicochemical soil properties and biotic factors. Nitrates and urea increased B. pseudomallei load in sand while phosphates had a positive effect in clay. The high buffering and cation exchange capacities of organic material found in a commercial potting mix led to a marked increase in soil salinity with no survival of B. pseudomallei after four weeks in the potting mix sampled. Imported grasses were also associated with B. pseudomallei occurrence in a multivariate model. With increasing population density in endemic areas these findings inform the identification of areas in the anthropogenic environment with increased risk of exposure to B. pseudomallei.
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