Evidence map›Paper›PMID 25802981›Full record

ArticleMolecular psychiatry2015

Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory.

P Li, D Rial, P M Canas, J-H Yoo, W Li, X Zhou, Y Wang, G J P van Westen, M-P Payen, E Augusto and 11 more

Abstract readPublished Erratum
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Adenosine and adenosine receptors in metabolic imbalance-related neurological issues.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024
    Review
  3. Adenosine AProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  4. Review
  5. Review
  6. Article
  7. Optical control of purinergic signaling.Purinergic signalling · 2021
    Review
  8. Article
  9. An Open Question: Is the AFrontiers in pharmacology · 2021
    Article
  10. Astrocytes and Adenosine AFrontiers in neuroscience · 2021
    Review
  11. Role of Adenosine in Epilepsy and Seizures.Journal of caffeine and adenosine research · 2020
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Adenosine ATranslational psychiatry · 2017
    Article
  17. Contrast media & molecular imaging · 2017
    Review
  18. Review
  19. Chemogenetic and Optogenetic Activation of Gαs Signaling in the Basolateral Amygdala Induces Acute and Social Anxiety-Like States.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016
    Article
  20. Optogenetic Activation of Adenosine A2A Receptor Signaling in the Dorsomedial Striatopallidal Neurons Suppresses Goal-Directed Behavior.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

P Li
D Rial
P M Canas
J-H Yoo
W Li
X Zhou
Y Wang
G J P van Westen
M-P Payen
E Augusto
N Gonçalves
A R Tomé
Z Li
Z Wu
X Hou
Y Zhou
Ad PIJzerman
E S Boyden
R A Cunha
J Qu
J-F Chen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID25802981

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.