Evidence map›Paper›PMID 25802979›Full record

ArticleEpidemiology and psychiatric sciences2016

The epidemiology of common mental disorders from age 20 to 50: results from the prospective Zurich cohort Study.

J Angst, D Paksarian, L Cui, K R Merikangas, M P Hengartner, V Ajdacic-Gross, W Rössler

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and psychiatric sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
15.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 84 citations in OpenAlex.

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  12. Bipolar disorders in ICD-11: current status and strengths.International journal of bipolar disorders · 2020
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  16. Bipolar spectrum in major depressive disorders.European archives of psychiatry and clinical neuroscience · 2018
    Article
  17. Usefulness of Pharmacogenetic Analysis in Psychiatric Clinical Practice: A Case Report.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

J AngstDepartment of Psychiatry, Psychotherapy and Psychosomatics,Psychiatric Hospital,University of Zurich.
D PaksarianGenetic Epidemiology Research Branch,Intramural Research Program,National Institute of Mental Health,Bethesda,Maryland.
L CuiGenetic Epidemiology Research Branch,Intramural Research Program,National Institute of Mental Health,Bethesda,Maryland.
K R MerikangasGenetic Epidemiology Research Branch,Intramural Research Program,National Institute of Mental Health,Bethesda,Maryland.
M P HengartnerDepartment of Psychiatry, Psychotherapy and Psychosomatics,Psychiatric Hospital,University of Zurich.
V Ajdacic-GrossDepartment of Psychiatry, Psychotherapy and Psychosomatics,Psychiatric Hospital,University of Zurich.
W RösslerDepartment of Psychiatry, Psychotherapy and Psychosomatics,Psychiatric Hospital,University of Zurich.
National Institute of Mental Health · USUniversity of Zurich · CHUniversity Psychiatric Hospital · SI

Funding

Zurich Cohort Study of Young AdultsZIAMH002807 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MERIKANGAS, KATHLEEN R · 2009 to 2015
$831k
6 · The paper itself

Abstract

backgroundThere are only a small number of prospective studies that have systematically evaluated standardised diagnostic criteria for mental disorder for more than a decade. The aim of this study is to present the approximated overall and sex-specific cumulative incidence of mental disorder in the Zurich cohort study, a prospective cohort study of 18-19 years olds from the canton of Zurich, Switzerland, who were followed through age 50.

methodA stratified sample of 591 participants were interviewed with the Structured Psychopathological Interview and Rating of the Social Consequences of Psychological Disturbances for Epidemiology, a semi-structured interview that uses a bottom-up approach to assess the past-year presence of 15 psychiatric syndromes. Seven interview waves took place between 1979 and 2008. Approximated cumulative incidence was estimated using Kaplan-Meier methods.

resultsRates of mental disorder were considerably higher than those generally reported in cross-sectional surveys. We found rates ranging from 32.5% for major depressive disorder to 1.2% for Bipolar I disorder. The cumulative probability of experiencing any of the mental disorders assessed by age 50 was 73.9%, the highest reported to date. We also found that rates differed by sex for most disorders, with females generally reporting higher rates of mood, anxiety and phobic disorder, and males reporting higher rates of substance- and alcohol-related disorders.

conclusionsThese findings confirm those of other long-term prospective studies that indicate the nearly universal nature of disturbances of emotion and behaviour across the life span. Greater community awareness of the normative nature of these experiences is warranted. An important area of future research is study long-term course and stability to determine who among those with such disturbances suffer from chronic disabling mental disorders. Such longitudinal studies may aid in directing services and intervention efforts where they are most needed.

Indexed as

AdultAnxiety DisordersCross-Sectional StudiesFemaleHumansMajor Depressive DisorderMaleMental DisordersMiddle AgedProspective StudiesSwitzerlandYoung AdultEpidemiologyprevalenceprospectivepsychiatric disorders

Identifiers

PMID25802979
PMCPMC6998675
OpenAlexW2054298320

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.