Evidence map›Paper›PMID 25802793›Full record

ArticleCase reports in surgery2015

A lethal complication after transarterial chemoembolization with drug-eluting beads for hepatocellular carcinoma.

Adriana Toro, Gaetano Bertino, Maria Concetta Arcerito, Maurizio Mannnino, Annalisa Ardiri, Domenico Patane', Isidoro Di Carlo

Abstract read
In one paragraph

Article in Case reports in surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adriana ToroDepartment of Surgical Sciences, Organ Transplantation and Advanced Technologies, University of Catania, Cannizzaro Hospital, 95100 Catania, Italy.
Gaetano BertinoDepartment of Internal Medicine and Systemic Disease, Hepatology Unit, University of Catania, S. Marta Hospital, 95100 Catania, Italy.ORCID 0000-0002-4557-2649
Maria Concetta ArceritoDepartment of Emergency, Vittorio Emanuele Hospital, 93012 Gela, Italy.
Maurizio MannninoDepartment of Surgical Sciences, Organ Transplantation and Advanced Technologies, University of Catania, Cannizzaro Hospital, 95100 Catania, Italy.
Annalisa ArdiriDepartment of Internal Medicine and Systemic Disease, Hepatology Unit, University of Catania, S. Marta Hospital, 95100 Catania, Italy.
Domenico Patane'Department of Radiology, Cannizzaro Hospital, 95100 Catania, Italy.
Isidoro Di CarloDepartment of Surgical Sciences, Organ Transplantation and Advanced Technologies, University of Catania, Cannizzaro Hospital, 95100 Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background. The current standard of care for patients with large or multinodular noninvasive hepatocellular carcinoma is conventional transarterial chemoembolization (TACE). TACE may also be performed with drug-eluting beads, but serious complications of this procedure have been reported. Methods. Aim of this report is to present a patient affected by multifocal HCC who underwent TACE with drug-eluting bead (DEB-TACE). Results. Following the procedure the patient developed a hepatic abscess and biliobronchial fistula resulting in adult respiratory distress syndrome and death. Conclusion. We speculate that DEB-TACE has a prolonged effect on the tumor and the surrounding liver, resulting in progressive enlargement of the necrotic area. This activity that can extend to the surrounding healthy hepatic tissues may continue indefinitely.

Identifiers

PMID25802793
PMCPMC4353438

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.