ArticleWorld journal of surgery2015
Papillary Thyroid Carcinoma in Children and Adolescents: Long-Term Follow-Up and Clinical Characteristics.
Article in World journal of surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- 2022 European Thyroid Association Guidelines for the management of pediatric thyroid nodules and differentiated thyroid carcinoma.European thyroid journal · 2022Guideline
- Paediatric differentiated thyroid carcinoma: a UK National Clinical Practice Consensus Guideline.Endocrine-related cancer · 2022Guideline
- Article
- Pediatric Thyroid Cancer Multidisciplinary Team Improves Adherence of Radioactive Iodine Treatment According to National Guidelines.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- Clinical characteristics and prognosis of histological subtypes of papillary thyroid carcinoma in pediatric patients.Endocrine oncology (Bristol, England) · 2025Article
- Concurrent Association of Multifocality, Bilaterality, and Recurrence in Pediatric Papillary Thyroid Cancer Patients.Yonsei medical journal · 2025Article
- Clinical features of thyroid cancer in paediatric age. Experience of a tertiary centre in the 2000-2020 period.Endocrine · 2023Article
- Primary presentation and clinical course of pediatric and adolescent patients with differentiated thyroid carcinoma after radioiodine therapy.Frontiers in oncology · 2023Article
- Ultrasound, laboratory and histopathological insights in diagnosing papillary thyroid carcinoma in a paediatric population: a single centre follow-up study between 2000-2022.Frontiers in endocrinology · 2023Article
- Comparison of ultrasonography and pathology features between children and adolescents with papillary thyroid carcinoma.Heliyon · 2023Article
- Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of AgeJournal of clinical research in pediatric endocrinology · 2022Review
- Epidemiology and treatment of head and neck malignancies in the AYA generation.International journal of clinical oncology · 2022Review
- Long-Term Oncological Outcomes of Papillary Thyroid Cancer and Follicular Thyroid Cancer in Children: A Nationwide Population-Based Study.Frontiers in endocrinology · 2022Article
- Clinical Heterogeneity of Differentiated Thyroid Cancer between Children Less than 10 Years of Age and Those Older than 10 Years: A Retrospective Study of 70 Cases.European thyroid journal · 2021Article
- Communicating with residents about 10 years of scientific progress in understanding thyroid cancer risk in children after the Fukushima Dai-ichi Nuclear Power Station accident.Journal of radiation research · 2021Article
- Radiofrequency Ablation for Cervical Metastatic Lymph Nodes in Children and Adolescents With Papillary Thyroid Carcinoma: A Preliminary Study.Frontiers in endocrinology · 2021Article
- Recommendations on Surveillance for Differentiated Thyroid Carcinoma in Children with PTEN Hamartoma Tumor Syndrome.European thyroid journal · 2020Review
- Cervical Lymph Node Metastases of Papillary Thyroid Carcinoma, in the Central and Lateral Compartments, in Children and Adolescents: Predictive Factors.World journal of surgery · 2018Article
- Comparison of differentiated thyroid carcinoma recurrence and its clinical features in children of different ages.Oncotarget · 2017Article
- Correlation between Ultrasound Elastography and Histologic Characteristics of Papillary Thyroid Carcinoma.Scientific reports · 2017Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to analyze the clinical features and clinical outcomes of papillary thyroid carcinoma (PTC) in the pediatric and adolescent population treated in our institution.
methodsThe subjects were 227 PTC patients 20 years of age or under treated initially between 1979 and 2012. Their mean age at diagnosis was 18-year old (range 7-20 years). Patient characteristics and outcomes in the period before 1999 and the period after 2000 were compared. Cause-specific survival (CSS) rates and disease-free survival (DFS) rates were calculated by the Kaplan-Meier method.
resultsTwo patients died of their disease and 45 patients had recurrent disease (36 in lymph node, seven in a remnant thyroid, and 11 in the form of distant metastasis). The 10-, 20-, and 30-CSS rates were 99.3, 99.3, and 96.5%, respectively, and the 10-, 20-, and 30-DFS were 83.6, 70.7, and 64.0%, respectively. Gender and preoperative lymph node metastasis were identified as significant factors related to DFS in the multivariate analysis. After the year 2000, there were significantly more patients with a small primary tumor size, significantly more patients without distant metastasis at presentation and significantly more patients without extrathyroidal invasion.
conclusionThe number of patients with advanced cancer has been declining in recent years. Lobectomy with prophylactic unilateral central neck dissection is considered acceptable for patients without the risk factors for recurrence.
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