Evidence map›Paper›PMID 25802165›Full record

ArticleThe Journal of emergency medicine2015

Correlation between Subclinical Heart Disease and Cardiovascular Risk Profiles in an Urban Emergency Department Population with Elevated Blood Pressures: A Pilot Study.

Heather M Prendergast, Joseph Colla, Neal Patel, Marina Del Rios, Jared Marcucci, Ryan Scholz, Patience Ngwang, Katherine Cappitelli, Martha Daviglus, Samuel Dudley

Open access · greenAbstract read
In one paragraph

Article in The Journal of emergency medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Hypertension in the Emergency Department.Current hypertension reports · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Heather M PrendergastDepartment of Emergency Medicine, University of Illinois, Chicago, Illinois.
Joseph CollaDepartment of Emergency Medicine, University of Illinois, Chicago, Illinois.
Neal PatelDepartment of Emergency Medicine, University of Illinois, Chicago, Illinois.
Marina Del RiosDepartment of Emergency Medicine, University of Illinois, Chicago, Illinois.
Jared MarcucciDepartment of Emergency Medicine, University of Illinois, Chicago, Illinois.
Ryan ScholzDepartment of Emergency Medicine, University of Illinois, Chicago, Illinois.
Patience NgwangDepartment of Emergency Medicine, University of Illinois, Chicago, Illinois.
Katherine CappitelliDepartment of Emergency Medicine, University of Illinois, Chicago, Illinois.
Martha DaviglusInstitute of Minority Health Research, University of Illinois, Chicago, Illinois.
Samuel DudleySection of Cardiology, Brown University, Providence, Rhode Island.
University of Illinois Chicago · USBrown University · USUniversity of Illinois Urbana-Champaign · US

Funding

Center for Clinical and Translational ScienceUL1TR000050 · NCATS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AZAR, DIMITRI T, MERMELSTEIN, ROBIN J. · 2012 to 2014
$9.8M
NCATS NIH HHS UL1 TR000050NCATS NIH HHS UL1TR000050
6 · The paper itself

Abstract

backgroundUncontrolled hypertension is a primary risk factor for development of cardiovascular complications.

objectiveDetermine the point prevalence of left ventricular hypertrophy (LVH) and diastolic dysfunction in an urban emergency department (ED) population with elevated blood pressures (BP) and examine correlations between subclinical disease and patient cardiovascular risk profiles.

methodsA convenience sample of patients with EBP (>140/90 on two measurements) had limited bedside echocardiograms (LBE). Subclinical hypertensive heart disease was classified as the presence of: LVH, abnormal ejection fraction (EF), or diastolic dysfunction.

resultsThirty-nine patients with EBP were enrolled. The mean age was 46 years (SD = 10.9), 59% were women, 21% were smokers, and 92% had a history of hypertension. The average body mass index was 30.7 (SD = 8.7). Patients were 67% African American, 23% Latino, 5% Caucasian, 3% Asian, and 3% Native American. Subclinical disease was found in 39%: 31% had LVH, 15% had diastolic dysfunction, and 8% had abnormal EF. On bivariate analysis, elevated BP (p = 0.039) and blood urea nitrogen (p = 0.016) were correlated with subclinical heart disease. After adjusting for other covariates, receiving oral/intravenous antihypertensive medications in the ED (p = 0.005) was associated with subclinical heart disease.

conclusionsWe found a point prevalence of subclinical heart disease of 39% in this urban ED population, using LBE. Real-time identification of subclinical heart disease at early stages in the ED in conjunction with abnormal renal function can help emergency physicians identify those patients in need of more aggressive therapy and urgent follow-up.

Indexed as

Blood PressureAdultAntihypertensive AgentsAsymptomatic DiseasesBlood Urea NitrogenDiastoleEmergency Service, HospitalFemaleHeart DiseasesHospitals, UrbanHumansHypertensionHypertrophy, Left VentricularMaleMiddle AgedPilot ProjectsAntihypertensive Agentselevated blood pressureemergency departmentemergency provider echocardiogramsubclinical heart disease

Identifiers

PMID25802165
PMCPMC4457673
OpenAlexW2068507595

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.