ArticleJournal of neurovirology2015
Multiple sclerosis and HIV-1 infection: case report of a HIV controller.
Article in Journal of neurovirology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Do Antiretroviral Drugs Protect From Multiple Sclerosis by Inhibiting Expression of MS-Associated Retrovirus?Frontiers in immunology · 2018Trial
- Fingolimod increases cellular resistance to HIV-1 infection and limits viral reservoir size in peripheral CD4+ T-cells.PLoS pathogens · 2026Article
- Viruses and neurodegeneration: a growing concern.Journal of translational medicine · 2025Review
- HIV infection and multiple sclerosis: a case with unexpected "no evidence of disease activity" status.The Journal of international medical research · 2021Article
- Acquisition of human immunodeficiency virus infection in a patient with multiple sclerosis: could these conditions positively influence each other's course?Journal of neurovirology · 2020Article
- Clinical Characteristics of HIV-Associated Optic Neuritis.International medical case reports journal · 2020Article
- Human immunodeficiency virus and multiple sclerosis: a review of the literature.Neurological research and practice · 2019Review
- Viruses and endogenous retroviruses in multiple sclerosis: From correlation to causation.Acta neurologica Scandinavica · 2017Review
- Down-regulation of interleukin 7 receptor (IL-7R) contributes to central nervous system demyelination.Oncotarget · 2017Article
- HIV and decreased risk of multiple sclerosis: role of low CD4+ lymphocyte count and male prevalence.Journal of neurovirology · 2017Article
- Cooccurrences of Putative Endogenous Retrovirus-Associated Diseases.BioMed research international · 2017Review
- A survey of endogenous retrovirus (ERV) sequences in the vicinity of multiple sclerosis (MS)-associated single nucleotide polymorphisms (SNPs).Molecular biology reports · 2016Article
- Two endogenous retroviral loci appear to contribute to Multiple Sclerosis.BMC neurology · 2016Review
- HIV immunodynamics and multiple sclerosis.Journal of neurovirology · 2016Article
- Multiple Sclerosis and Subsequent Human Immunodeficiency Virus Infection: A Case with the Rare Comorbidity, Focus on Novel Treatment Issues and Review of the Literature.In vivo (Athens, Greece)Review
Corrections and comments
- Commented on by
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple sclerosis (MS) has been infrequently described in association with human immunodeficiency virus (HIV) infection. Underreporting, missed diagnoses or a true negative association between MS and HIV infection are all possible explanations for the paucity of published cases. Since MS involves inflammation and demyelination of the central nervous system by autoreactive T cells, immunosuppression caused by HIV infection would be expected to confer a reduced risk of MS. This report describes a case of relapsing-remitting MS in a woman with non-progressive HIV-1 infection for 5 years. The patient has stable normal CD4+ cell counts and a low viral load in the absence of combination antitretroviral treatment (cART). She experienced typical neurological symptoms of MS including optic neuritis, trigeminal neuralgia, and transverse myelitis. MRI of the spinal cord demonstrated multiple lesions on T2-weighted images. Immune mechanisms associated with HIV control that may have contributed to the development and relapses of MS in this patient are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.