Evidence map›Paper›PMID 25801558›Full record

ArticleAntimicrobial agents and chemotherapy2015

Trends in susceptibility of Escherichia coli from intra-abdominal infections to ertapenem and comparators in the United States according to data from the SMART program, 2009 to 2013.

Sibylle H Lob, Krystyna M Kazmierczak, Robert E Badal, Meredith A Hackel, Samuel K Bouchillon, Douglas J Biedenbach, Daniel F Sahm

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 106 citations in OpenAlex.

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  6. In vitro activity of aztreonam-avibactam against Enterobacterales isolates collected in Latin America, Africa/Middle East, Asia, and Eurasia for the ATLAS Global Surveillance Program in 2019-2021.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Article
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  12. Review
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  18. Evaluation of theJAC-antimicrobial resistance · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sibylle H LobInternational Health Management Associates, Inc., Schaumburg, Illinois, USA shlob@ihmainc.com.
Krystyna M KazmierczakInternational Health Management Associates, Inc., Schaumburg, Illinois, USA.
Robert E BadalInternational Health Management Associates, Inc., Schaumburg, Illinois, USA.
Meredith A HackelInternational Health Management Associates, Inc., Schaumburg, Illinois, USA.
Samuel K BouchillonInternational Health Management Associates, Inc., Schaumburg, Illinois, USA.
Douglas J BiedenbachInternational Health Management Associates, Inc., Schaumburg, Illinois, USA.
Daniel F SahmInternational Health Management Associates, Inc., Schaumburg, Illinois, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance in Enterobacteriaceae, including resistance to carbapenems, is increasing worldwide. However, using U.S. Study for Monitoring Antimicrobial Resistance Trends (SMART) data for 2009 to 2013, no statistically significant decreasing susceptibility trends were found overall for Escherichia coli isolates from patients with intra-abdominal infections. In the subset of isolates from community-associated infections, susceptibility to levofloxacin decreased significantly and the increasing rate of multidrug-resistant E. coli approached statistical significance. In 2013, ertapenem, imipenem, and amikacin showed the highest susceptibility rates (≥99%) and fluoroquinolones the lowest (<70%). The 10 non-ertapenem-susceptible isolates (0.3% of all E. coli isolates) encoded one or more carbapenemases, extended-spectrum β-lactamases (ESBLs), AmpC β-lactamases, or non-ESBL β-lactamases.

Indexed as

Anti-Bacterial Agentsbeta-Lactamasesbeta-LactamsErtapenemEscherichia coliGenotypeHumansIntraabdominal InfectionsMicrobial Sensitivity TestsUnited StatesAnti-Bacterial Agentsbeta-Lactamasesbeta-LactamsErtapenem

Identifiers

PMID25801558
PMCPMC4432174
OpenAlexW2116644484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.