Evidence map›Paper›PMID 25801236›Full record

ReviewClinical pharmacology and therapeutics2015

Medicinal chemistry of cannabinoids.

V Kiran Vemuri, A Makriyannis

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical pharmacology and therapeutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 108 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Development and Early Identification of Cannabis Chemotypes during the Plant Growth: Current Analytical and Chemometric Approaches.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021
    Review
  8. Article
  9. The Role of Organic Small Molecules in Pain Management.Molecules (Basel, Switzerland) · 2021
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Cannabinoid disruption of learning mechanisms involved in reward processing.Learning & memory (Cold Spring Harbor, N.Y.) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

V Kiran VemuriCenter for Drug Discovery, Northeastern University, Boston, Massachusetts, USA.
A MakriyannisCenter for Drug Discovery, Northeastern University, Boston, Massachusetts, USA.
King Abdulaziz University · SANortheastern University · US

Funding

Project 3 - In vivo pharmacology of cannabinoid receptor probesP01DA009158 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI Alexandros Makriyannis · 1994 to 2026
$26.0M
Cannabinergic Medications for Methamphetamine AddictionR37DA023142 · NIDA · NORTHEASTERN UNIVERSITY · PI MAKRIYANNIS, ALEXANDROS · 2007 to 2016
$7.1M
NIDA NIH HHS P01 DA009158NIDA NIH HHS R37 DA023142
6 · The paper itself

Abstract

The endocannabinoid system comprises the two well characterized Gi/o -protein coupled receptors (cannabinoid receptor 1 (CB1) and CB2), their endogenous lipid ligands, and the enzymes involved in their biosynthesis and biotransformation. Drug discovery efforts relating to the endocannabinoid system have been focused mainly on the two cannabinoid receptors and the two endocannabinoid deactivating enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGL). This review provides an overview of cannabinergic agents used in drug research and those being explored clinically.

Indexed as

AmidohydrolasesCannabinoidsChemistry, PharmaceuticalDrug DiscoveryFatty Acid Amide HydrolasesHumansMonoacylglycerol LipasesReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2AmidohydrolasesCannabinoidsFatty Acid Amide HydrolasesMonoacylglycerol LipasesReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2

Identifiers

PMID25801236
PMCPMC4918805
OpenAlexW1997944001

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.