ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2015
Increased risk of coronary heart disease in patients with hip fracture: a nationwide cohort study.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Bidirectional association between cardiovascular disease and hip fracture: a systematic review and meta-analysis.BMC cardiovascular disorders · 2025Pooled it
- Incidence and risk factors for stroke after hip fracture: a meta-analysis.Scientific reports · 2023Pooled it
- Relationship Between Low Bone Mineral Density and Fractures With Incident Cardiovascular Disease: A Systematic Review and Meta-Analysis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2017Pooled it
- First-week postoperative caloric intake predicts mortality, complications and functional recovery in elderly patients with hip fracture and compromised nutritional status.Journal of health, population, and nutrition · 2026Observational
- Review
- Postoperative mortality following hip fracture surgery in older adults: a single-center retrospective study in the context of Taiwan's transition to an aged society.Scientific reports · 2025Article
- Risk factors and prognosis of perioperative acute heart failure in elderly patients with hip fracture: case-control studies and cohort study.BMC musculoskeletal disorders · 2024Article
- Cardiac alterations following experimental hip fracture - inflammaging as independent risk factor.Frontiers in immunology · 2022Article
- Trauma, a Matter of the Heart-Molecular Mechanism of Post-Traumatic Cardiac Dysfunction.International journal of molecular sciences · 2021Review
- Systemic and Cardiac Alterations After Long Bone Fracture.Shock (Augusta, Ga.) · 2020Article
- Risks of acute coronary syndrome in patients with osteoarthritis: a nationwide population-based cohort study.Clinical rheumatology · 2016Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledThe study indicates that hip fracture is independently associated with increased risk of coronary heart disease. In addition, the highest risk of coronary heart disease following hip fracture appeared within the first year after hip fracture, indicating the need for multidisciplinary care for the patients.
introductionBone and vasculature are modulated through numerous common pathways. However, data on the risk of coronary heart disease (CHD) after hip fracture are scarce. Therefore, we investigated whether hip fracture increased the risk of CHD by conducting a large nationwide cohort study.
methodsUsing universal insurance claims data from 2000 to 2010, we identified a study cohort of 6013 participants newly diagnosed with hip fracture and a control cohort of 23,802 participants. Both cohorts were followed up to the end of 2011 to evaluate the risk of CHD.
resultsThe overall incidence of CHD was 1.69-fold higher in the hip fracture cohort than it was in the control cohort (29.2 vs. 17.1 per 1000 person-years) with an adjusted hazard ratio of 1.51 (95 % confidence interval [CI] = 1.39-1.65). Sex-, age-, and comorbidity-specific analyses showed a higher relative risk of CHD for both women and men, all age groups, those with and without comorbidities, and patients with hip fracture compared with the control cohort. The highest risk of CHD was within the first year after hip fracture (adjusted HR = 1.72, 95 % CI = 1.45-2.04), and the risk remained high in the following years.
conclusionHip fracture was independently associated with a subsequent risk of CHD.
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