ArticleScientific reports2015
Portable microfluidic integrated plasmonic platform for pathogen detection.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
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Who cites it
58 citing papers in PubMed.
- A Comparison of Cost-Effective Sensors for a Fluorescence-Based Detection System Used in Biodiagnostic Devices.Biosensors · 2026Article
- Advances in biosensors for bacterial detection and identification.World journal of microbiology & biotechnology · 2025Review
- Nanophotonics in Molecular Imaging and Biomedicine: Diagnostics, Therapies, and Translational Challenges.Molecular imaging and biology · 2025Review
- Integrated Photonic Biosensors: Enabling Next-Generation Lab-on-a-Chip Platforms.Nanomaterials (Basel, Switzerland) · 2025Review
- Towards Point-of-Care Single Biomolecule Detection Using Next Generation Portable Nanoplasmonic Biosensors: A Review.Biosensors · 2024Review
- Microfluidics for detection of food pathogens: recent trends and opportunities.Journal of food science and technology · 2024Review
- Shedding Light on Cellular Secrets: A Review of Advanced Optical Biosensing Techniques for Detecting Extracellular Vesicles with a Special Focus on Cancer Diagnosis.ACS applied bio materials · 2024Review
- Analysis of Fluid Replacement in Two Fluidic Chambers for Oblique-Incidence Reflectivity Difference (OI-RD) Biosensor.Sensors (Basel, Switzerland) · 2024Article
- Immuno-SPR biosensor for the detection of Brucella abortus.Scientific reports · 2023Article
- Healthcare provider-targeted mobile applications to diagnose, screen, or monitor communicable diseases of public health importance in low- and middle-income countries: A systematic review.PLOS digital health · 2023Article
- Point-of-Care Diagnostic Devices for Detection ofBiosensors · 2023Review
- Aptamer-Based Point-of-Care Devices: Emerging Technologies and Integration of Computational Methods.Biosensors · 2023Review
- Polymeric and Paper-Based Lab-on-a-Chip Devices in Food Safety: A Review.Micromachines · 2023Review
- Single-cell pathogen diagnostics for combating antibiotic resistance.Nature reviews. Methods primers · 2023Article
- Leveraging microfluidic dielectrophoresis to distinguish compositional variations of lipopolysaccharide inFrontiers in bioengineering and biotechnology · 2023Article
- Recent Progress and Challenges on the Microfluidic Assay of Pathogenic Bacteria Using Biosensor Technology.Biomimetics (Basel, Switzerland) · 2022Review
- Materials Perspectives of Integrated Plasmonic Biosensors.Materials (Basel, Switzerland) · 2022Review
- Recent advancements in microfluidic chip biosensor detection of foodborne pathogenic bacteria: a review.Analytical and bioanalytical chemistry · 2022Review
- A Review of Optical Imaging Technologies for Microfluidics.Micromachines · 2022Review
- Simultaneous Absorbance and Fluorescence Measurements Using an Inlaid Microfluidic Approach.Sensors (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Timely detection of infectious agents is critical in early diagnosis and treatment of infectious diseases. Conventional pathogen detection methods, such as enzyme linked immunosorbent assay (ELISA), culturing or polymerase chain reaction (PCR) require long assay times, and complex and expensive instruments, which are not adaptable to point-of-care (POC) needs at resource-constrained as well as primary care settings. Therefore, there is an unmet need to develop simple, rapid, and accurate methods for detection of pathogens at the POC. Here, we present a portable, multiplex, inexpensive microfluidic-integrated surface plasmon resonance (SPR) platform that detects and quantifies bacteria, i.e., Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) rapidly. The platform presented reliable capture and detection of E. coli at concentrations ranging from ~10(5) to 3.2 × 10(7) CFUs/mL in phosphate buffered saline (PBS) and peritoneal dialysis (PD) fluid. The multiplexing and specificity capability of the platform was also tested with S. aureus samples. The presented platform technology could potentially be applicable to capture and detect other pathogens at the POC and primary care settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.