Evidence map›Paper›PMID 25800679›Full record

ArticleAngewandte Chemie (International ed. in English)2015

Alkyl Aryl Ether Bond Formation with PhenoFluor.

Xiao Shen, Constanze N Neumann, Claudia Kleinlein, Nathaniel W Goldberg, Tobias Ritter

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Synthetic Studies Towards Darobactin A.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Efficient O-Functionalization of Carbohydrates with Electrophilic Reagents.Angewandte Chemie (International ed. in English) · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiao ShenDepartment of Chemistry and Chemical Biology, Harvard University, 12 Oxford St., Cambridge, MA 02138 (USA) http://www.rittergroup.org.
Constanze N Neumann
Claudia Kleinlein
Nathaniel W Goldberg
Tobias Ritter

Funding

Organometallic Chemistry for Applications in Biomedical SciencesR01GM088237 · NIGMS · HARVARD UNIVERSITY · PI RITTER, TOBIAS · 2010 to 2016
$2.5M
NIGMS NIH HHS R01 GM088237
6 · The paper itself

Abstract

An alkyl aryl ether bond formation reaction between phenols and primary and secondary alcohols with PhenoFluor has been developed. The reaction features a broad substrate scope and tolerates many functional groups, and substrates that are challenging for more conventional ether bond forming processes may be coupled. A preliminary mechanistic study indicates reactivity distinct from conventional ether bond formation.

Indexed as

AlcoholsEthersImidazolinesMolecular StructureAlcoholsEthersImidazolinesPhenoFluoralkyl aryl ethersCO bond formationfluorineMitsunobu reactionPhenoFluor

Identifiers

PMID25800679
PMCPMC4487836

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.