Evidence map›Paper›PMID 25800089›Full record

ArticleGut microbes2015

Exercise and the microbiota.

Orla O'Sullivan, Owen Cronin, Siobhan F Clarke, Eileen F Murphy, Micheal G Molloy, Fergus Shanahan, Paul D Cotter

Registry-linked trialAbstract read
In one paragraph

Article in Gut microbes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03325933 (Resistance Training and Cardiometabolic Health), which is not on this map. Cited by 82 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03325933 naterminatednot on this mapstarted 2017, after this paper: background citation

Resistance Training and Cardiometabolic Health

TypeinterventionalSponsorArizona State UniversityRan2017 to 2020Enrolled62ConditionsInsulin Sensitivity, Endothelial Dysfunction, Blood PressureArmsHigh Load/Low Rep Resistance Training, Low Load/High Rep Resistance Training
3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Science advances · 2023
    Trial
  5. Exercise Training Modulates Gut Microbiota Profile and Improves Endotoxemia.Medicine and science in sports and exercise · 2020
    Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Review
  11. Article
  12. Training load influences gut microbiome of highly trained rowing athletes.Journal of the International Society of Sports Nutrition · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Orla O'Sullivana Teagasc Food Research Center ; Moorepark; Fermoy; Cork , Ireland.
Owen Cronin
Siobhan F Clarke
Eileen F Murphy
Micheal G Molloy
Fergus Shanahan
Paul D Cotter

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sedentary lifestyle is linked with poor health, most commonly obesity and associated disorders, the corollary being that exercise offers a preventive strategy. However, the scope of exercise biology extends well beyond energy expenditure and has emerged as a great 'polypill', which is safe, reliable and cost-effective not only in disease prevention but also treatment. Biological mechanisms by which exercise influences homeostasis are becoming clearer and involve multi-organ systemic adaptations. Most of the elements of a modern lifestyle influence the indigenous microbiota but few studies have explored the effect of increased physical activity. While dietary responses to exercise obscure the influence of exercise alone on gut microbiota, professional athletes operating at the extremes of performance provide informative data. We assessed the relationship between extreme levels of exercise, associated dietary habits and gut microbiota composition, and discuss potential mechanisms by which exercise may exert a direct or indirect influence on gut microbiota.

Indexed as

ExerciseFeeding BehaviorGastrointestinal MicrobiomeMicrobiotaAthletesDietHumansdietdiversityexercisegut microbiotahost-microbe interactions

Identifiers

PMID25800089
PMCPMC4615660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.