ArticleThe Journal of cell biology1985
Proteins transported in slow components a and b of axonal transport are distributed differently in the transverse plane of the axon.
Article in The Journal of cell biology, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 30 citations in OpenAlex.
- Fodrin in centrosomes: implication of a role of fodrin in the transport of gamma-tubulin complex in brain.PloS one · 2013Article
- Cytoskeletal requirements in axonal transport of slow component-b.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008Article
- Functional analysis of dynactin and cytoplasmic dynein in slow axonal transport.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1996Article
- Transport complexes associated with slow axonal flow.Neurochemical research · 1991Review
- Progressive and spatially differentiated stability of microtubules in developing neuronal cells.The Journal of cell biology · 1989Article
- Two classes of actin microfilaments are associated with the inner cytoskeleton of axons.The Journal of cell biology · 1988Article
- Rapidly transported organelles containing membrane and cytoskeletal components: their relation to axonal growth.The Journal of cell biology · 1987Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The distribution of the proteins migrating with the slow components a (SCa) and b (SCb) of axonal transport were studied in cross-sections of axons with electron microscope autoradiography. Radiolabeled amino acids were injected into the hypoglossal nucleus of rabbits and after 15 d, the animals were killed. Hypoglossal nerves were processed either for SDS-polyacrylamide gel electrophoresis fluorography to identify and locate the two components of slow transport, or for quantitative electron microscope autoradiography. Proteins transported in SCa were found to be uniformly distributed within the cross-section of the axon. Labeled SCb proteins were also found throughout the axonal cross-section, but the subaxolemmal region of the axon contained 2.5 times more SCb radioactivity than any comparable area in the remainder of the axon.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.