ArticleBone marrow transplantation2015
Changes in intensive care for allogeneic hematopoietic stem cell transplant recipients.
Article in Bone marrow transplantation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03449953 (Critical Care Outcomes of Patients With Hematologic Malignancy and Hematopoietic Cell Transplantation), which is not on this map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Critical Care Outcomes of Patients With Hematologic Malignancy and Hematopoietic Cell Transplantation
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Changes in critically ill cancer patients' short-term outcome over the last decades: results of systematic review with meta-analysis on individual data.Intensive care medicine · 2019Pooled it
- Critically ill allogenic HSCT patients in the intensive care unit: a systematic review and meta-analysis of prognostic factors of mortality.Bone marrow transplantation · 2018Pooled it
- Consensus statement for cancer patients requiring intensive care support.Annals of hematology · 2018Guideline
- Critical care illness in allogeneic hematopoietic stem-cell transplantation recipients with chronic graft versus host disease.Critical care (London, England) · 2025Article
- Contemporary review of critical illness following allogeneic hematopoietic stem cell transplant in adults.Intensive care medicine · 2025Review
- Patients admitted in the intensive care unit after solid organ or bone marrow transplantation: Retrospective cohort study.World journal of transplantation · 2025Article
- What intensivists need to know about cytomegalovirus infection in immunocompromised ICU patients.Intensive care medicine · 2025Review
- Clinical characteristics and outcomes of immunocompromised critically ill patients with cytomegalovirus end-organ disease: a multicenter retrospective cohort study.Critical care (London, England) · 2024Observational
- Can We Predict Acute Respiratory Distress Syndrome in Hematopoietic Stem Cell Recipients?American journal of respiratory and critical care medicine · 2024Article
- AKI treated with kidney replacement therapy in critically Ill allogeneic hematopoietic stem cell transplant recipients.Bone marrow transplantation · 2024Article
- Impact of chronic graft-versus-host-disease on intensive care outcome in allogeneic hematopoietic stem cell recipients.Bone marrow transplantation · 2023Article
- Clinical diagnostic accuracy of respiratory failure in critically ill hematopoietic stem cell transplant patients.International journal of hematology · 2022Article
- Article
- Allogeneic stem cell transplant recipients admitted to the intensive care unit during the peri-transplant period have unfavorable outcomes-results of a retrospective analysis from a German university hospital.Annals of hematology · 2022Article
- Outcome of allogeneic hematopoietic stem cell transplant recipients admitted to the intensive care unit with a focus on haploidentical graft and sequential conditioning regimen: results of a retrospective study.Annals of hematology · 2021Article
- Critically ill cancer patient's resuscitation: a Belgian/French societies' consensus conference.Intensive care medicine · 2021Article
- Acute Respiratory Distress Syndrome following Hematopoietic Stem Cell Transplantation: One More Piece in the Puzzle.Annals of the American Thoracic Society · 2021Article
- [Bone marrow transplantation patients in the intensive care unit].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2021Review
- Poor outcome associated with mucormycosis in critically ill hematological patients: results of a multicenter study.Annals of intensive care · 2021Article
- Trajectories of acute graft-versus-host disease and mortality in critically ill allogeneic-hematopoietic stem cell recipients: the Allo-GRRR-OH score.Bone marrow transplantation · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intensive care unit (ICU) admission is associated with high mortality in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Whether mortality has decreased recently is unknown. The 497 adult allogeneic HSCT recipients admitted to three ICUs between 1997 and 2011 were evaluated retrospectively. Two hundred and nine patients admitted between 1997 and 2003 were compared with the 288 patients admitted from 2004 to 2011. Factors associated with 90-day mortality were identified. The recent cohort was characterized by older age, lower conditioning intensity, and greater use of peripheral blood or unrelated-donor graft. In the recent cohort, ICU was used more often for patients in hematological remission (67% vs 44%; P<0.0001) and without GVHD (73% vs 48%; P<0.0001) or invasive fungal infection (85% vs 73%; P=0.0003) despite a stable admission rate (21.7%). These changes were associated with significantly better 90-day survival (49% vs 31%). Independent predictors of hospital mortality were GVHD, mechanical ventilation (MV) and renal replacement therapy (RRT). Among patients who required MV or RRT, survival was 29% and 18%, respectively, but dropped to 18% and 6% in those with GVHD. The use of ICU admission has changed and translated into improved survival, but advanced life support in patients with GVHD usually provides no benefits.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.