Evidence map›Paper›PMID 25798672›Full record

ReviewBone marrow transplantation2015

Indications for allo- and auto-SCT for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2015.

A Sureda, P Bader, S Cesaro, P Dreger, R F Duarte, C Dufour, J H F Falkenburg, D Farge-Bancel, A Gennery, N Kröger and 7 more

Registry-linked trialOpen access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Bone marrow transplantation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04727827 (A Prospective Interventional Trial of Pharmacogenomic-Guided Supportive Care in Hematopoietic Cell Transplantation), which is not on this map. Cited by 130 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed, 4 pooled it
28.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04727827 nacompletednot on this mapstarted 2021, after this paper: background citation

A Prospective Interventional Trial of Pharmacogenomic-Guided Supportive Care in Hematopoietic Cell Transplantation

TypeinterventionalSponsorWake Forest University Health SciencesRan2021 to 2023Enrolled110ConditionsHematopoietic Cell Transplantation, OncologyArmsPharmacogenomic-guided supportive care
3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 4 syntheses or guidelines pooled it, 332 citations in OpenAlex.

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  14. Patients' symptoms and challenges during the first year after allogeneic haematopoietic cell transplantation-patients' own expressions.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 14 institutions in 8 countries.

A SuredaDepartment of Haematology, Institut Catala d'Oncologia, Hospital Duran I Reynals, Barcelona, Spain.
P BaderUniversitätsklinikum Frankfurt, Goethe-Universität, Klinik für Kinder- und Jugendmedizin, Frankfurt, Germany.
S CesaroPaediatric Haematology Oncology, Policlinico G.B. Rossi, Verona, Italy.
P DregerDepartment of Internal Medicine V, University of Heidelberg, Heidelberg, Germany.
R F DuarteDepartment of Haematology, Institut Catala d'Oncologia, Hospital Duran I Reynals, Barcelona, Spain.
C DufourClinical And Experimental Hematology Unit. Institute G. Gaslini, Genoa, Italy.
J H F FalkenburgDepartment of Haematology, Leiden University Medical Center, Leiden, The Netherlands.
D Farge-BancelDepartment of Haematology-BMT, Hopital St Louis, Paris, France.
A GenneryChildren's BMT Unit, Great North Children's Hospital, Newcastle-Upon-Tyne, UK.
N KrögerDepartment of Stem Cell Transplantation, University hospital Eppendorf, Hamburg, Germany.
F LanzaHaematology and BMT Unit, Cremona, Italy.
J C MarshDepartment of Haematological Medicine, King's College Hospital/King's College London, London, UK.
A NaglerChaim Sheva Medical Center, Tel-Hashomer, Israel.
C PetersStem Cell Transplantation Unit, St Anna Kinderspital, Vienna, Austria.ORCID 0000000303698515
A VelardiSezione di Ematologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Perugia, Perugia, Italy.
M MohtyDepartment of Haematology, H. Saint Antoine, Paris, France.
A MadrigalAnthony Nolan Research Institute, Royal Free and University College, London, UK.
Institut Català d'Oncologia · ESAnthony Nolan · GBEppendorf (Germany) · DEGoethe University Frankfurt · DEGreat North Children's Hospital · GBHeidelberg University · DEHôpital Saint-Louis · FRIstituto Giannina Gaslini · ITKing's College London · GBLeiden University Medical Center · NLSheba Medical Center · ILSorbonne Université · FRSt Anna Children's Hospital · ATUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is the sixth special report that the European Society for Blood and Marrow Transplantation regularly publishes on the current practice and indications for haematopoietic SCT for haematological diseases, solid tumours and immune disorders in Europe. Major changes have occurred in the field of haematopoietic SCT over the last years. Cord blood units as well as haploidentical donors have been increasingly used as stem cell sources for allo-SCT, thus, augmenting the possibility of finding a suitable donor for a patient. Continuous refinement of conditioning strategies has also expanded not only the number of potential indications but also has permitted consideration of older patients or those with co-morbidity for a transplant. There is accumulating evidence of the role of haematopoietic SCT in non-haematological disorders such as autoimmune diseases. On the other hand, the advent of new drugs and very effective targeted therapy has challenged the role of SCT in some instances or at least, modified its position in the treatment armamentarium of a given patient. An updated report with revised tables and operating definitions is presented.

Indexed as

Tissue DonorsAllograftsAutograftsAutoimmune DiseasesDonor SelectionEuropeFemaleHematologic NeoplasmsHematopoietic Stem Cell TransplantationHumansMaleNeoplasms

Identifiers

PMID25798672
OpenAlexW2044804132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.