Trial reportPloS one2015
Limitations of stroke volume estimation by non-invasive blood pressure monitoring in hypergravity.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04369976 (Estimating the Optimal G Level for Training and Rehabilitation on a Short Arm Human Centrifuge), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Estimating the Optimal G Level for Training and Rehabilitation on a Short Arm Human Centrifuge
Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Indirect measurement of absolute cardiac output during exercise in simulated altered gravity is highly dependent on the method.Journal of clinical monitoring and computing · 2022Article
- A Cardiac Force Index Applied to the G Tolerance Test and Surveillance among Male Military Aircrew.International journal of environmental research and public health · 2021Article
- Combined effect of heart rate responses and the anti-G straining manoeuvre effectiveness on G tolerance in a human centrifuge.Scientific reports · 2020Article
- Intermittent Calf Compression Delays the Onset of Presyncope in Young Healthy Individuals.Frontiers in physiology · 2019Article
- Short-Term Cardiovascular Response to Short-Radius Centrifugation With and Without Ergometer Exercise.Frontiers in physiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAltitude and gravity changes during aeromedical evacuations induce exacerbated cardiovascular responses in unstable patients. Non-invasive cardiac output monitoring is difficult to perform in this environment with limited access to the patient. We evaluated the feasibility and accuracy of stroke volume estimation by finger photoplethysmography (SVp) in hypergravity.
methodsFinger arterial blood pressure (ABP) waveforms were recorded continuously in ten healthy subjects before, during and after exposure to +Gz accelerations in a human centrifuge. The protocol consisted of a 2-min and 8-min exposure up to +4 Gz. SVp was computed from ABP using Liljestrand, systolic area, and Windkessel algorithms, and compared with reference values measured by echocardiography (SVe) before and after the centrifuge runs.
resultsThe ABP signal could be used in 83.3% of cases. After calibration with echocardiography, SVp changes did not differ from SVe and values were linearly correlated (p<0.001). The three algorithms gave comparable SVp. Reproducibility between SVp and SVe was the best with the systolic area algorithm (limits of agreement -20.5 and +38.3 ml).
conclusionsNon-invasive ABP photoplethysmographic monitoring is an interesting technique to estimate relative stroke volume changes in moderate and sustained hypergravity. This method may aid physicians for aeronautic patient monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.