Evidence map›Paper›PMID 25798444›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2014

Diagnostic potential of multimodal imaging of ovarian tissue using optical coherence tomography and second-harmonic generation microscopy.

Weston A Welge, Andrew T DeMarco, Jennifer M Watson, Photini S Rice, Jennifer K Barton, Matthew A Kupinski

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Journal of biomedical optics · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Weston A WelgeThe University of Arizona, College of Optical Sciences, 1630 E. University Blvd. Tucson, AZ 85721, 303-875-5632.
Andrew T DeMarcoThe University of Arizona, Department of Speech, Language, and Hearing Sciences, 1131 E. 2nd St. Tucson, AZ 85721, 267-474-0513.
Jennifer M WatsonThe University of Arizona, Department of Biomedical Engineering, 1657 E. Helen St. Tucson, AZ 85721, 520-626-2917.
Photini S RiceThe University of Arizona, Department of Biomedical Engineering, 1657 E. Helen St. Tucson, AZ 85721, 520-626-4463.
Jennifer K BartonThe University of Arizona, College of Optical Sciences, Department of Biomedical Engineering, 1657 E. Helen St. Tucson, AZ 85721, 520-626-4116.
Matthew A KupinskiThe University of Arizona, College of Optical Sciences, 1630 E. University Blvd. Tucson, AZ 85721, 520-621-2967.

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Justin M Snider · 1985 to 2026
$110.2M
Cardiovascular Biomedical Engineering Training GrantT32HL007955 · NHLBI · UNIVERSITY OF ARIZONA · PI BARTON, JENNIFER KEHLET · 2001 to 2020
$5.1M
Optical Imaging of Ovarian Carcinogenesis in a Rat Menopause ModelR01CA119200 · NCI · UNIVERSITY OF ARIZONA · PI BARTON, JENNIFER KEHLET · 2007 to 2011
$1.7M
NCI NIH HHS P30 CA023074NCI NIH HHS R01 CA119200NHLBI NIH HHS T32 HL007955
6 · The paper itself

Abstract

Ovarian cancer is particularly deadly because it is usually diagnosed after it has metastasized. We have previously identified features of ovarian cancer using optical coherence tomography (OCT) and second-harmonic generation (SHG) microscopy (targeting collagen). OCT provides an image of the ovarian microstructure while SHG provides a high-resolution map of collagen fiber bundle arrangement. Here we investigated the diagnostic potential of dual-modality OCT and SHG imaging. We conducted a fully crossed, multi-reader, multi-case study using seven human observers. Each observer classified 44

Indexed as

image qualitymultimodal imagingoptical coherence tomographyovarian cancersecond harmonic generation

Identifiers

PMID25798444
PMCPMC4365797

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.