ArticleAnesthesiology and pain medicine2014
Comparing the efficacy of intravenous acetaminophen and intravenous meperidine in pain relief after outpatient urological surgery.
Article in Anesthesiology and pain medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The trial behind it
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Efficacy of scheduled intravenous acetaminophen administration for catheter-related bladder discomfort in patients after transurethral resection of bladder tumors: A prospective randomized pilot study.Investigative and clinical urology · 2025Trial
- Postoperative around-the-clock administration of intravenous acetaminophen for pain control following robot-assisted radical prostatectomy.Scientific reports · 2021Article
- Design and psychometrics cultural competence questionnaire for health promotion of Iranian nurses.Journal of education and health promotion · 2019Article
- Comparison of the Analgesic Effect of Paracetamol and Magnesium Sulfate during Surgeries.World journal of plastic surgery · 2016Article
- Intravenous Paracetamol Versus Patient-Controlled Analgesia With Morphine for the Pain Management Following Diagnostic Knee Arthroscopy in Trauma Patients: A Randomized Clinical Trial.Archives of trauma research · 2015Article
- Premedication With Single Dose of Acetazolamide for the Control of Referral Shoulder Pain After Laparoscopic Cholecystectomy.Anesthesiology and pain medicine · 2015Article
- A Comparison of Patient Controlled Epidural Analgesia With Intravenous Patient Controlled Analgesia for Postoperative Pain Management After Major Gynecologic Oncologic Surgeries: A Randomized Controlled Clinical Trial.Anesthesiology and pain medicine · 2015Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPain relief after surgery is an essential component of postoperative care.
objectivesThe purpose of this study was to compare the efficacy of intravenous acetaminophen and intravenous meperidine in pain relief after outpatient urological surgery. PATIENTS AND
methodsIn a prospective, randomized, double-blind clinical trial, 100 outpatients of urological surgery were studied in two groups of acetaminophen (A) and meperidine (M). Patients in group A received 1g of acetaminophen in 100 mL saline within 15 minutes and patients in group M received a single intravenous injection of meperidine 0.5 mg/kg, 15 minutes prior to the end of operation. Postoperative pain was recorded using visual analog scale (VAS). Vital signs, nausea, vomiting, dizziness and respiratory depressions were compared between the two groups.
resultsPain severity in patients treated with intravenous acetaminophen six hours after the operation within one-hour interval was significantly lower than meperidine group (P < 0.0001). Ninety patients in the meperidine group and five patients in the acetaminophen group required additional doses of analgesics. Nausea was significantly lower in acetaminophen group than meperidine group.
conclusionsIntravenous acetaminophen reduced pain following outpatient urological surgery more significantly than meperidine.
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