Evidence map›Paper›PMID 25798318›Full record

ArticleBiomedical optics express2015

Biodynamic imaging of live porcine oocytes, zygotes and blastocysts for viability assessment in assisted reproductive technologies.

Ran An, Chunmin Wang, John Turek, Zoltan Machaty, David D Nolte

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Investigation of refractive index dynamics duringBiomedical optics express · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Biodynamic optical assay for embryo viability.Journal of biomedical optics · 2019
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ran AnDept. of Physics, Purdue University, West Lafayette IN 47907 USA.
Chunmin WangDept. of Animal Sciences, Purdue University, West Lafayette IN 47907 USA.
John TurekDept. of Basic Medical Sciences, Purdue University, West Lafayette IN 47907 USA.
Zoltan MachatyDept. of Animal Sciences, Purdue University, West Lafayette IN 47907 USA.
David D NolteDept. of Physics, Purdue University, West Lafayette IN 47907 USA.
Purdue University West Lafayette · US

Funding

Tissue-dynamics Imaging for Therapeutic Efficacy in Ovarian CancerR01EB016582 · NIBIB · PURDUE UNIVERSITY · PI MATEI, DANIELA E, NOLTE, DAVID D · 2013 to 2016
$1.3M
NIBIB NIH HHS R01 EB016582
6 · The paper itself

Abstract

The success of assisted reproductive technologies relies on accurate assessment of reproductive viability at successive stages of development for oocytes and embryos. The current scoring system used to select good-quality oocytes relies on morphologically observable traits and hence is indirect and subjective. Biodynamic imaging may provide an objective approach to oocyte and embryo assessment by measuring physiologically-relevant dynamics. Biodynamic imaging is a coherence-gated approach to 3D tissue imaging that uses digital holography to perform low-coherence speckle interferometry to capture dynamic light scattering from intracellular motions. The changes in intracellular activity during cumulus oocyte complex maturation, before and after in vitro fertilization, and the subsequent development of the zygote and blastocyst provide a new approach to the assessment of preimplant candidates.

Indexed as

(090.0090) Holography(090.1995) Digital holography(170.0170) Medical optics and biotechnology(170.3880) Medical and biological imaging

Identifiers

PMID25798318
PMCPMC4361448
OpenAlexW1973777816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.