ArticleQuantitative biology (Beijing, China)2013
Personal genomes, quantitative dynamic omics and personalized medicine.
Article in Quantitative biology (Beijing, China), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02654704 (Vaccination Responses in Young and Older Adults), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Vaccination Responses in Young and Older Adults
Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
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- Longitudinal personal DNA methylome dynamics in a human with a chronic condition.Nature medicine · 2018Article
- Precision medicine in diabetes: an opportunity for clinical translation.Annals of the New York Academy of Sciences · 2018Review
- MathIOmica: An Integrative Platform for Dynamic Omics.Scientific reports · 2016Article
- Use of the "Exposome" in the Practice of Epidemiology: A Primer on -Omic Technologies.American journal of epidemiology · 2016Article
- A systematic study on drug-response associated genes using baseline gene expressions of the Cancer Cell Line Encyclopedia.Scientific reports · 2016Article
- Metabolome progression during early gut microbial colonization of gnotobiotic mice.Scientific reports · 2015Article
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- Toward more transparent and reproducible omics studies through a common metadata checklist and data publications.Omics : a journal of integrative biology · 2014Article
- Integrative analysis of longitudinal metabolomics data from a personal multi-omics profile.Metabolites · 2013Article
- Whole-exome sequencing identifies tetratricopeptide repeat domain 7A (TTC7A) mutations for combined immunodeficiency with intestinal atresias.The Journal of allergy and clinical immunology · 2013Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The rapid technological developments following the Human Genome Project have made possible the availability of personalized genomes. As the focus now shifts from characterizing genomes to making personalized disease associations, in combination with the availability of other omics technologies, the next big push will be not only to obtain a personalized genome, but to quantitatively follow other omics. This will include transcriptomes, proteomes, metabolomes, antibodyomes, and new emerging technologies, enabling the profiling of thousands of molecular components in individuals. Furthermore, omics profiling performed longitudinally can probe the temporal patterns associated with both molecular changes and associated physiological health and disease states. Such data necessitates the development of computational methodology to not only handle and descriptively assess such data, but also construct quantitative biological models. Here we describe the availability of personal genomes and developing omics technologies that can be brought together for personalized implementations and how these novel integrated approaches may effectively provide a precise personalized medicine that focuses on not only characterization and treatment but ultimately the prevention of disease.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.