Evidence map›Paper›PMID 25797757›Full record

Trial reportJournal of the American College of Surgeons2015

A novel risk scoring system reliably predicts readmission after pancreatectomy.

Vicente Valero, Joshua C Grimm, Arman Kilic, Russell L Lewis, Jeffrey J Tosoian, Jin He, James F Griffin, John L Cameron, Matthew J Weiss, Charles M Vollmer and 2 more

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American College of Surgeons, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Specialty-Specific Readmission Risk Models Outperform General Models in Estimating Hepatopancreatobiliary Surgery Readmission Risk.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  4. Article
  5. Article
  6. Specific Medicare Severity-Diagnosis Related Group Codes Increase the Predictability of 30-Day Unplanned Hospital Readmission After Pancreaticoduodenectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2018
    Article
  7. Comparing early and delayed repair of common bile duct injury to identify clinical drivers of outcome and morbidity.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2016
    Article
  8. Investigating Transitional Care to Decrease Post-pancreatectomy 30-Day Hospital Readmissions for Dehydration or Failure to Thrive.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2016
    Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Vicente ValeroDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD.
Joshua C GrimmDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD.
Arman KilicDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD.
Russell L LewisDepartment of Surgery, The University of Pennsylvania School of Medicine, Philadelphia, PA.
Jeffrey J TosoianDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD.
Jin HeDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD.
James F GriffinDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD.
John L CameronDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD.
Matthew J WeissDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD.
Charles M VollmerDepartment of Surgery, The University of Pennsylvania School of Medicine, Philadelphia, PA.
Christopher L WolfgangDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address: cwolfga2@jhmi.edu.
Pancreas Readmission Assessment Group Study
Johns Hopkins University · USJohns Hopkins Medicine · USUniversity of Pennsylvania · US

Funding

Clinical and Laboratory Research Training for Gastrointestinal SurgeonsT32DK007713 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI DAVID J HACKAM · 1996 to 2026
$5.2M
NIDDK NIH HHS T32 DK007713
6 · The paper itself

Abstract

backgroundPostoperative readmissions have been proposed by Medicare as a quality metric and can impact provider reimbursement. Because readmission after pancreatectomy is common, we sought to identify factors associated with readmission to establish a predictive risk scoring system. STUDY

designA retrospective analysis of 2,360 pancreatectomies performed at 9 high-volume pancreatic centers between 2005 and 2011 was performed. Forty-five factors strongly associated with readmission were identified. To derive and validate a risk scoring system, the population was randomly divided into 2 cohorts in a 4:1 fashion. A multivariable logistic regression model was constructed and scores were assigned based on the relative odds ratio (OR) of each independent predictor. A composite Readmission after Pancreatectomy (RAP) score was generated and then stratified to create risk groups.

resultsOverall, 464 (19.7%) patients were readmitted within 90 days. Eight pre- and postoperative factors, including earlier MI (OR = 2.03), American Society of Anesthesiologists class ≥ 3 (OR = 1.34), dementia (OR = 6.22), hemorrhage (OR = 1.81), delayed gastric emptying (OR = 1.78), surgical site infection (OR = 3.31), sepsis (OR = 3.10), and short length of stay (OR = 1.51) were independently predictive of readmission. The 32-point RAP score generated from the derivation cohort was highly predictive of readmission in the validation cohort (area under the receiver operating curve = 0.72). The low-risk (0 to 3), intermediate-risk (4 to 7), and high-risk (>7) groups correlated with 11.7%, 17.5%, and 45.4% observed readmission rates, respectively (p < 0.001).

conclusionsThe RAP score is a novel and clinically useful risk scoring system for readmission after pancreatectomy. Identification of patients with increased risk of readmission using the RAP score will allow efficient resource allocation aimed to attenuate readmission rates. It also has potential to serve as a new metric for comparative research and quality assessment.

Indexed as

FemaleFollow-Up StudiesHumansMaleMiddle AgedMorbidityOdds RatioPancreatectomyPancreatic DiseasesPatient ReadmissionPostoperative ComplicationsPredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsTime Factors

Identifiers

PMID25797757
PMCPMC4452114
OpenAlexW1998188288

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.