Evidence map›Paper›PMID 25796596›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2015

Virtualization of open-source secure web services to support data exchange in a pediatric critical care research network.

Lewis J Frey, Katherine A Sward, Christopher J L Newth, Robinder G Khemani, Martin E Cryer, Julie L Thelen, Rene Enriquez, Su Shaoyu, Murray M Pollack, Rick E Harrison and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Pediatric Multiple Organ Dysfunction Syndrome: Promising Therapies.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2017
    Review
  3. Precision medicine informatics.Journal of the American Medical Informatics Association : JAMIA · 2016
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Lewis J FreyBiomedical Informatics Center, Department Public Health Sciences, Medical University of South Carolina, Charleston, USA frey@musc.edu.
Katherine A SwardCollege of Nursing; Department of Biomedical Informatics, University of Utah, Salt Lake City, USA.
Christopher J L NewthUSC Keck School of Medicine; Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, USA.
Robinder G KhemaniUSC Keck School of Medicine; Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, USA.
Martin E CryerDepartment of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, USA.
Julie L ThelenDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, USA.
Rene EnriquezDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, USA.
Su ShaoyuDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, USA.
Murray M PollackPhoenix Children's Hospital, Department of Pediatrics, University of Arizona Phoenix, Phoenix, USA.
Rick E HarrisonDepartment of Pediatrics, University of California at Los Angeles, Los Angeles, USA.
Kathleen L MeertDepartment of Pediatrics, Children's Hospital of Michigan, Detroit, USA.
Robert A BergDepartment of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
David L WesselDepartment of Pediatrics, Children's National Medical Center, Washington, DC, USA.
Thomas P ShanleyDepartment of Pediatrics, University of Michigan, Ann Arbor, USA.
Heidi DaltonDepartment of Child Health, Phoenix Children's Hospital, University of Arizona College of Medicine-Phoenix, Phoenix, USA.
Joseph CarcilloDepartment of Critical Care Medicine, Children's Hospital of Pittsburgh, Pittsburgh, USA.
Tammara L JenkinsEunice Kennedy Shriver National Institutes of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, USA.
J Michael DeanDepartment of Pediatrics, Division of Pediatric Critical Care Medicine, University of Utah School of Medicine; NICHD Collaborative Pediatric Critical Care Research Network, Salt Lake City, USA.

Funding

Data Coordinating Center for the Collaborative Pediatric Critical Care Research NetworkU01HD049934 · NICHD · UNIVERSITY OF UTAH · PI DEAN, JONATHAN MICHAEL · 2005 to 2020
$35.2M
Physiologically Guided Ventilator Strategies in ChildrenU10HD050012 · NICHD · CHILDREN'S HOSPITAL OF LOS ANGELES · PI NEWTH, CHRISTOPHER JOHN · 2005 to 2014
$3.7M
Neurodevelopmental Outcome after Cardiac Intensive CareU10HD049981 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI WESSEL, DAVID LLOYD · 2005 to 2014
$3.7M
Collaborative Pediatric Critical Care Research NetworkU10HD050096 · NICHD · WAYNE STATE UNIVERSITY · PI MEERT, KATHLEEN L. · 2005 to 2014
$3.2M
Metoclopramide prevents PICU nosocomial infectionU10HD049983 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CARCILLO, JOSEPH A · 2005 to 2014
$3.1M
Collaborative Pediatric Critical Care Research Network (CPCCRN) at Children's NationalUG1HD049981 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI POLLACK, MURRAY MICHAEL, WESSEL, DAVID LLOYD · 2015 to 2020
$1.8M
Pediatric Critical Care Research Network at Children's Hospital of PhiladelphiaUG1HD063108 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI BERG, ROBERT ALLEN, ZUPPA, ATHENA F. · 2015 to 2020
$1.7M
Collaborative Pediatric Critical Care Research NetworkUG1HD050096 · NICHD · WAYNE STATE UNIVERSITY · PI MEERT, KATHLEEN L. · 2015 to 2020
$1.6M
Pediatric Critical Care Research Network at Children's Hospital of PhiladelphiaU10HD063108 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI BERG, ROBERT ALLEN · 2010 to 2014
$1.4M
Predicting Morbidity from Pediatric Critical CareU10HD063114 · NICHD · PHOENIX CHILDREN'S HOSPITAL · PI DALTON, HEIDI J, LUND, DENNIS P · 2010 to 2014
$1.4M
Collaborative Pediatric Research Critical Care Network(U10)U10HD063106 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SHANLEY, THOMAS P. · 2010 to 2014
$1.3M
Collaborative Pediatric Critical Care Research Network - Clinical SiteRL1HD107773 · NICHD · CENTRAL MICHIGAN UNIVERSITY · PI KATHLEEN L. MEERT · 2021 to 2026
$862k
NICHD NIH HHS RL1 HD107773NICHD NIH HHS U01 HD049934NICHD NIH HHS U01HD049934NICHD NIH HHS U10 HD049981NICHD NIH HHS U10HD049981NICHD NIH HHS U10 HD049983NICHD NIH HHS U10HD049983NICHD NIH HHS U10 HD050012NICHD NIH HHS U10HD050012NICHD NIH HHS U10 HD050096NICHD NIH HHS U10HD050096NICHD NIH HHS U10 HD063106NICHD NIH HHS U10HD063106NICHD NIH HHS U10 HD063108NICHD NIH HHS U10HD063108NICHD NIH HHS U10 HD063114NICHD NIH HHS U10HD063114NICHD NIH HHS UG1 HD049981NICHD NIH HHS UG1 HD050096NICHD NIH HHS UG1 HD063108
6 · The paper itself

Abstract

objectivesTo examine the feasibility of deploying a virtual web service for sharing data within a research network, and to evaluate the impact on data consistency and quality. MATERIAL AND

methodsVirtual machines (VMs) encapsulated an open-source, semantically and syntactically interoperable secure web service infrastructure along with a shadow database. The VMs were deployed to 8 Collaborative Pediatric Critical Care Research Network Clinical Centers.

resultsVirtual web services could be deployed in hours. The interoperability of the web services reduced format misalignment from 56% to 1% and demonstrated that 99% of the data consistently transferred using the data dictionary and 1% needed human curation.

conclusionsUse of virtualized open-source secure web service technology could enable direct electronic abstraction of data from hospital databases for research purposes.

Indexed as

Access to InformationComputer Communication NetworksCritical CareInternetComputer SystemsDatabases as TopicFeasibility StudiesHumansInformation DisseminationPediatricsSoftwaredata governanceelectronic health recordgridlearning health care systempediatric critical carepediatric networksecure web servicesvirtualizationvirtual machines

Identifiers

PMID25796596
PMCPMC4639713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.