ReviewHeart failure reviews2015
Left ventricular assist devices: a kidney's perspective.
Review in Heart failure reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence and impact of acute kidney injury on patients with implantable left ventricular assist devices: a Meta-analysis.Renal failure · 2020Pooled it
- Perioperative clinical profiles and longitudinal outcomes in patients supported by continuous-flow left ventricular assist devices: a comprehensive analysis of early and late follow-up data.Frontiers in cardiovascular medicine · 2026Article
- Risk factors and in-hospital outcomes of acute kidney injury requiring continuous renal replacement therapy after left ventricular assist device implantation.SAGE open medicine · 2026Article
- Preoperative Albumin-Bilirubin (ALBI) Score Is the Strongest Predictor of Mortality After LVAD Implantation.Biomedicines · 2025Article
- Acute kidney injury and chronic kidney disease after left ventricular assist device placement.JTCVS open · 2025Article
- Peritoneal Dialysis in Patients Supported by Left Ventricular Assist Device.Artificial organs · 2025Article
- Article
- Management of patients with heart failure and chronic kidney disease.Heart failure reviews · 2024Review
- Impact of gender in patients with continuous-flow left ventricular assist device therapy in end-stage heart failure.The International journal of artificial organs · 2021Article
- Heart transplant candidate with medical complexity in the era of prolonged left ventricular assist device support - A case report.Journal of cardiology cases · 2021Article
- Renal Outcomes in Patients Bridged to Heart Transplant With a Left Ventricular Assist Device.The Annals of thoracic surgery · 2020Article
- Post-operative renal failure management in mechanical circulatory support patients.Annals of translational medicine · 2020Review
- Article
- Pediatric Ventricular Assist Device.Korean circulation journal · 2019Review
- The mid-term effect of left ventricular assist devices on renal functions.Turk gogus kalp damar cerrahisi dergisi · 2019Article
- Acute kidney injury after implantation of a left ventricular assist device: a comparison of axial-flow (HeartMate II) and centrifugal-flow (HeartWare HVAD) devices.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2018Article
- The influence of less invasive ventricular assist device implantation on renal function.Journal of thoracic disease · 2018Article
- Perioperative Enteral Nutrition After Left Ventricular Assist Device Implantation.Nutrition and metabolic insights · 2018Article
- Reversible preoperative renal dysfunction does not add to the risk of postoperative acute kidney injury after cardiac valve surgery.Therapeutics and clinical risk management · 2017Article
- Calciotropic and Phosphaturic Hormones in End-Stage Heart Failure Patients Supported by a Left-Ventricular Assist Device.PloS one · 2016Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The left ventricular assist device (LVAD) has become an established treatment option for patients with refractory heart failure. Many of these patients experience chronic kidney disease (CKD) due to chronic cardiorenal syndrome type II, which is often alleviated quickly following LVAD implantation. Nevertheless, reversibility of CKD remains difficult to predict. Interestingly, initial recovery of GFR appears to be transient, being followed by gradual but significant late decline. Nevertheless, GFR often remains elevated compared to preimplant status. Larger GFR increases are followed by a proportionally larger late decline. Several explanations for this gradual decline in renal function after LVAD therapy have been proposed, yet a definitive answer remains elusive. Mortality predictors of LVAD implantation are the occurrence of either postimplantation acute kidney injury (AKI) or preimplant CKD. However, patient outcomes continue to improve as LVAD therapy becomes more widespread, and adverse events including AKI appear to decline. In light of a growing destination therapy population, it is important to understand the cumulative effects of long-term LVAD support on kidney function. Additional research and passage of time are required to further unravel the intricate relationships between the LVAD and the kidney.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.