Evidence map›Paper›PMID 25795015›Full record

ArticlePublic health2015

Tuberculosis report among injection drug users and their partners in Kazakhstan.

S Hermosilla, N El-Bassel, A Aifah, A Terlikbayeva, Z Zhumadilov, K Berikkhanova, M Darisheva, L Gilbert, N Schluger, S Galea

Open access · greenAbstract read
In one paragraph

Article in Public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Prisoners co-infected with tuberculosis and HIV: a systematic review.Journal of the International AIDS Society · 2016
    Pooled it
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  3. Review
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  9. Review
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  11. Risks for tuberculosis in Kazakhstan: implications for prevention.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2017
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

S HermosillaColumbia University Medical Center, USA. Electronic address: sh2405@columbia.edu.
N El-BasselColumbia University School of Social Work, USA.
A AifahColumbia University School of Social Work, USA.
A TerlikbayevaGlobal Health Research Center of Central Asia, USA.
Z ZhumadilovNazarbayev University, Kazakhstan.
K BerikkhanovaNazarbayev University, Kazakhstan.
M DarishevaGlobal Health Research Center of Central Asia, USA.
L GilbertColumbia University School of Social Work, USA.
N SchlugerColumbia University Medical Center, USA.
S GaleaColumbia University Medical Center, USA.
Columbia University Irving Medical Center · USGlobal Health Research Center of Central Asia · USNazarbayev University · KZUniversity School · USColumbia University · US

Funding

Couples-Based HIV/STI Prevention for Injecting Drug Users in KazakhstanR01DA022914 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI EL-BASSEL, NABILA · 2008 to 2012
$3.3M
NIDA NIH HHS 1R01DA022914NIDA NIH HHS R01 DA022914
6 · The paper itself

Abstract

objectivesTuberculosis (TB) is a major threat to global public health. Kazakhstan has the second highest percentage of multidrug-resistant tuberculosis (MDR-TB) cases among incident tuberculosis cases in the world (WHO 2013). A high burden of MDR-TB suggests TB prevention, control, and treatment programs are failing. This study provides an epidemiologic profile of TB among injection drug users (IDUs), a high-risk and chronically underserved population, in Kazakhstan. STUDY

designCross-sectional study.

methodsThe authors studied the characteristics and risk environment of IDUs with self-reported previous active TB and their primary sexual partners in Almaty, Kazakhstan. 728 individuals (364 couples) participated in a couple-based study in 2009.

results16.75% of participants reported at least one positive TB test (x-ray) in their lifetime. In a multivariable logistic regression adjusting for couple-based sampling, persons with positive TB test were significantly more likely to be older (odds ratio (OR) 7.26, 95% confidence interval (CI): 1.73, 30.43), male (OR 5.53, 95% CI: 2.74, 11.16), have a shorter duration of injection drug use (OR 0.17, 95% CI: 0.04, 0.65), have received high social support from their significant other (OR 2.13, 95% CI: 1.03, 4.40) and more likely (non-significantly) to have been incarcerated (OR 7.03, 95% CI: 0.64, 77.30).

conclusionsOlder men with a history of incarceration and recent injection drug use were more likely to have positive TB test in Kazakhstan. Social network support, while potentially positive for many aspects of population health, may increase risk of TB among IDUs in this context. Public health policies that target high-risk populations and their at-risk networks may be necessary to stem the rise of MDR-TB in Central Asia.

Indexed as

Sexual PartnersAdultAge DistributionCross-Sectional StudiesDrug UsersFemaleHumansKazakhstanLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrisonersRisk FactorsSex DistributionSocial SupportCentral AsiaIncarcerationInjection drug usersKazakhstanSocial supportTuberculosis

Identifiers

PMID25795015
PMCPMC7829468
OpenAlexW2105153340

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.