Evidence map›Paper›PMID 25795013›Full record

Trial reportJournal of abnormal child psychology2016

Effects of Adolescent Universal Substance Misuse Preventive Interventions on Young Adult Depression Symptoms: Mediational Modeling.

Linda Trudeau, Richard Spoth, W Alex Mason, G Kevin Randall, Cleve Redmond, Lisa Schainker

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of abnormal child psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Brief, Non-Pharmacological, Interventions for Pediatric Anxiety: Meta-Analysis and Evidence Base Status.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Pooled it
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  4. Trial
  5. Reducing Internalizing Symptoms Among High-Risk, Hispanic Adolescents: Mediators of a Preventive Family Intervention.Prevention science : the official journal of the Society for Prevention Research · 2016
    Trial
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linda TrudeauPartnerships in Prevention Science Institute, Iowa State University, 2625 N. Loop Drive, Suite 2400, Ames, IA, 50010, USA. ltrudeau@iastate.edu.
Richard SpothPartnerships in Prevention Science Institute, Iowa State University, 2625 N. Loop Drive, Suite 2400, Ames, IA, 50010, USA.
W Alex MasonBoys Town National Research Institute for Child and Family Studies, 14100 Crawford Street, Boys Town, NE, 68010, USA.
G Kevin RandallPartnerships in Prevention Science Institute, Iowa State University, 2625 N. Loop Drive, Suite 2400, Ames, IA, 50010, USA.
Cleve RedmondPartnerships in Prevention Science Institute, Iowa State University, 2625 N. Loop Drive, Suite 2400, Ames, IA, 50010, USA.
Lisa SchainkerPartnerships in Prevention Science Institute, Iowa State University, 2625 N. Loop Drive, Suite 2400, Ames, IA, 50010, USA.

Funding

RURAL YOUTH AND FAMILY COMPETENCIES BUILDING PROJECTR37DA010815 · NIDA · IOWA STATE UNIVERSITY · PI SPOTH, RICHARD · 1997 to 2006
$8.0M
RURAL YOUTH AND FAMILY COMPETENCIES BUILDING PROJECTSR01DA010815 · NIDA · IOWA STATE UNIVERSITY · PI SPOTH, RICHARD · 1999 to 2013
$3.3M
NIDA NIH HHS DA 010815NIDA NIH HHS L30 DA018511NIDA NIH HHS R01 DA010815NIDA NIH HHS R37 DA010815
6 · The paper itself

Abstract

Depression symptoms are associated with impairments in functioning and have substantial health and economic consequences. Universal substance misuse prevention programs have shown effects on non-targeted mental health-related symptoms, but long-term effects are understudied. This cluster randomized controlled trial examined effects of both the LifeSkills Training (LST) and Strengthening Families Program: For Parents and Youth 10-14 (SFP 10-14) interventions, delivered during seventh grade, on age 22 young adult depression symptoms. The study was conducted in US rural Midwestern communities with a randomly-selected sample from a larger study (N = 670). Experimental conditions were LST+SFP 10-14, LST-only, and a control condition. Effects on age 22 depression symptoms were hypothesized as mediated through effects on age 21 relationship problems and illicit use of substances. Structural equation modeling with manifest and latent variables was conducted to test hypotheses; the intervention conditions were combined and compared with the control condition because analyses indicated a comparable pattern of effects between intervention conditions. Significant indirect intervention effects were found on age 22 depression symptoms via effects on the mediating variables (indirect effect: β = -0.06, 95 % CI [-0.10, -0.01], p = 0.011). Effect sizes for the young adult variables were between d = 0.17 and 0.29, which can be considered small, but nontrivial, especially in the context of public health benefits. Results support scaled-up implementation of school-based and family-focused universal substance misuse preventive interventions.

Indexed as

Outcome Assessment, Health CareAdolescentAdultDepressionFamily TherapyFemaleFollow-Up StudiesHumansMaleMidwestern United StatesModels, PsychologicalPsychotherapyRural PopulationSubstance-Related DisordersYoung AdultDepression symptomsMediationPreventive interventionYoung adult

Identifiers

PMID25795013
PMCPMC4598302

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.