Evidence map›Paper›PMID 25794800›Full record

ReviewAcademic radiology2015

Pitfalls in RECIST Data Extraction for Clinical Trials: Beyond the Basics.

Richard G Abramson, Carrie R McGhee, Nikita Lakomkin, Carlos L Arteaga

Abstract readReview
In one paragraph

Review in Academic radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 37 citations in OpenAlex.

  1. Trial
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  15. What scans we will read: imaging instrumentation trends in clinical oncology.Cancer imaging : the official publication of the International Cancer Imaging Society · 2020
    Review
  16. Article
  17. Developing global image feature analysis models to predict cancer risk and prognosis.Visual computing for industry, biomedicine, and art · 2019
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Richard G AbramsonVanderbilt University School of Medicine, Department of Radiology and Radiological Science, 1161 21st Avenue South, CCC-1121 MCN, Nashville, TN 37232-2675. Electronic address: richard.abramson@vanderbilt.edu.
Carrie R McGheeVanderbilt University School of Medicine, Department of Radiology and Radiological Science, 1161 21st Avenue South, CCC-1121 MCN, Nashville, TN 37232-2675.
Nikita LakomkinVanderbilt University School of Medicine, Department of Radiology and Radiological Science, 1161 21st Avenue South, CCC-1121 MCN, Nashville, TN 37232-2675.
Carlos L ArteagaVanderbilt-Ingram Cancer Center, Nashville, Tennessee.
Vanderbilt University · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8M
TISSUE CoreP50CA098131 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PARK, BEN HO, PIETENPOL, JENNIFER A · 2003 to 2024
$48.7M
NCI NIH HHS P30 CA068485NCI NIH HHS P50 CA098131
6 · The paper itself

Abstract

Response Evaluation Criteria in Solid Tumors (RECIST) is a standardized methodology for determining therapeutic response to anticancer therapy using changes in lesion appearance on imaging studies. Many radiologists are now using RECIST in their routine clinical workflow, as part of consultative arrangements, or within dedicated imaging core laboratories. Although basic RECIST methodology is well described in published articles and online resources, inexperienced readers may encounter difficulties with certain nuances and subtleties of RECIST. This article illustrates a set of pitfalls in RECIST assessment considered to be "beyond the basics." These pitfalls were uncovered during a quality improvement review of a recently established cancer imaging core laboratory staffed by radiologists with limited prior RECIST experience. Pitfalls are presented in four categories: (1) baseline selection of lesions, (2) reassessment of target lesions, (3) reassessment of nontarget lesions, and (4) identification of new lesions. Educational and operational strategies for addressing these pitfalls are suggested. Attention to these pitfalls and strategies may improve the overall quality of RECIST assessments performed by radiologists.

Indexed as

Clinical Trials as TopicResponse Evaluation Criteria in Solid TumorsClinical CompetenceHumansNeoplasmsantitumor efficacyOncologyRECISTsolid malignanciestumor response assessment

Identifiers

PMID25794800
PMCPMC4429002
OpenAlexW78668827

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.