Evidence map›Paper›PMID 25794688›Full record

ArticleInternational journal of legal medicine2015

The auditory ossicles as a DNA source for genetic identification of highly putrefied cadavers.

Thorsten Schwark, Jan-Hendrik Modrow, Elena Steinmeier, Micaela Poetsch, Johannes Hasse, Hartmut Fischer, Nicole von Wurmb-Schwark

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Article in International journal of legal medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Thorsten SchwarkLudwig Boltzmann Institute for Clinical-Forensic Imaging, Universitätsplatz 4/2, 8010, Graz, Austria, thorsten.schwark@cfi.lbg.ac.at.
Jan-Hendrik Modrow
Elena Steinmeier
Micaela Poetsch
Johannes Hasse
Hartmut Fischer
Nicole von Wurmb-Schwark
University of Lübeck · DELudwig Boltzmann Institute for COPD And Respiratory Epidemiology · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic identification of putrefied bodies is a common task in forensic medicine. With advancing putrefaction, however, DNA integrity is rapidly decreasing and genetic typing of tissue might be impaired or impossible. Since DNA stability is generally higher in hard tissues, bones or teeth are frequently used as DNA source in such cases. However, isolation of DNA from hard tissues is usually very time-consuming and labor-intensive. This can be especially important in (forensic) cases where time is short and identification has to be carried out as fast as possible. Here, we present the identification of dead bodies by analyzing DNA from the auditory ossicles. These minuscule bones provided DNA of sufficient quality and quantity for identification purposes in all 40 investigated cases. Additionally, processing of the bones proved to be amazingly easy and fast, and a successful extraction is possible using a variety of different methods. We present a detailed protocol, results, and cases in which this new method has been successfully applied.

Indexed as

PedigreePostmortem ChangesAdultAgedAged, 80 and overDNA FingerprintingEar OssiclesFemaleForensic GeneticsHumansMaleMicrosatellite RepeatsMiddle AgedPolymerase Chain ReactionReproducibility of ResultsYoung Adult

Identifiers

PMID25794688
OpenAlexW2079065876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.