Evidence map›Paper›PMID 25793978›Full record

ArticlePloS one2015

Cardiovascular disease rates, outcomes, and quality of care in Ontario Métis: a population-based cohort study.

Clare L Atzema, Saba Khan, Hong Lu, Yvon E Allard, Storm J Russell, Mario R Gravelle, Julie Klein-Geltink, Peter C Austin

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  4. Atrial fibrillation in the Americas.Lancet regional health. Americas · 2025
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  8. Prevalence and clinical features of heart failure in Greenland.International journal of circumpolar health · 2023
    Article
  9. Article
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  11. Review
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  13. Article
  14. Review
  15. Article
  16. Acute health care among Indigenous patients in Canada: a scoping review.International journal of circumpolar health · 2021
    Article
  17. Article
  18. Elevated Blood Pressure and Associations with Sodium Intake Among Multiethnic Youth in Edmonton, Canada: Findings from WHY ACT NOW.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Clare L AtzemaInstitute for Clinical Evaluative Sciences, Toronto, Ontario, Canada; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada.
Saba KhanInstitute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.
Hong LuInstitute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.
Yvon E AllardThe Métis Nation of Ontario, Ottawa, Ontario, Canada.
Storm J RussellThe Métis Nation of Ontario, Ottawa, Ontario, Canada.
Mario R GravelleThe Métis Nation of Ontario, Ottawa, Ontario, Canada.
Julie Klein-GeltinkInstitute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.
Peter C AustinInstitute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.
Institute for Clinical Evaluative Sciences · CAMétis National Council · CAHealth Sciences Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe burden of cardiovascular disease in the Métis, Canada's fastest growing Aboriginal group, is not well studied. We determined rates of five cardiovascular diseases and associated outcomes in Ontario Métis, compared to the general Ontario population.

methodsMétis persons were identified using the Métis Nation of Ontario Citizenship Registry. Métis citizens aged 20-105 were linked to Ontario health databases for the period of April 2006 to March 2011. Age- and sex-standardized prevalence and incidence of acute coronary syndromes (ACS), congestive heart failure (CHF), cerebrovascular disease (stroke), atrial fibrillation, and hypertension were compared between the Métis and the general population. Secondary outcome measures included one-year hospitalizations and mortality following the incident cardiovascular diagnosis, as well as quality-of-care measures.

resultsThere were 12,550 eligible Métis persons and 10,144,002 in the general population. The adjusted prevalence of each disease was higher (p<0.05) among the Métis compared to the general population: ACS 5.3% vs. 3.0%; CHF 5.1% vs. 3.9%; stroke 1.4% vs. 1.1%; atrial fibrillation 2.1% vs. 1.4%; hypertension 34.9% vs. 29.8%. Incident ACS, stroke, and atrial fibrillation were also higher (p<0.05) among the Métis: ACS 2.4% vs. 1.5%; stroke 0.8% vs. 0.6%; atrial fibrillation 0.6% vs. 0.3%. One-year all-cause and cardiovascular-related mortality were not significantly different. Hospitalizations were higher for Métis persons with CHF (OR 1.93; 95% CI 1.34-2.78) and hypertension (OR 2.27; 95% CI 1.88-2.74). Métis with CHF made more emergency department (ED) visits in the year after diagnosis compared to non-Métis with CHF, while Métis aged ≥65 with ACS were more likely to be on beta-blockers following diagnosis.

conclusionsThe burden of cardiovascular disease was markedly higher in the Métis compared to the general population: prevalence rates for five cardiovascular conditions were 25% to 77% higher. Métis persons with CHF had more frequent hospitalizations and ED visits following their diagnosis.

Indexed as

Quality of Health CareAdultCardiovascular DiseasesCohort StudiesDemographyEthnicityFemaleHospitalizationHumansIncidenceMaleMiddle AgedOntarioPrevalenceTreatment Outcome

Identifiers

PMID25793978
PMCPMC4368556
OpenAlexW2090509539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.