Evidence map›Paper›PMID 25793961›Full record

ReviewFEMS microbiology reviews2015

Exceptionally widespread nanomachines composed of type IV pilins: the prokaryotic Swiss Army knives.

Jamie-Lee Berry, Vladimir Pelicic

Abstract readReview
In one paragraph

Review in FEMS microbiology reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 156 papers.

0numbers the graph read from it
0cells of the map it votes in
156citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

156 citing papers in PubMed.

  1. Two D-loop resolution systems enable natural genetic transformation in bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Review
  4. mBio · 2026
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  6. Article
  7. Article
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  9. Article
  10. Article
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  14. Cryo-EM structure of the conjugation H-pilus reveals the cyclic nature of the TrhA pilin.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. How Does the Archaellum Work?Biomolecules · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Type IV pili ofEcoSal Plus · 2024
    Review
  20. Article

96 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jamie-Lee BerryMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London SW7 2AZ, UK.
Vladimir PelicicMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London SW7 2AZ, UK v.pelicic@imperial.ac.uk.

Funding

Biotechnology and Biological Sciences Research CouncilMedical Research Council MR/J006874/1Medical Research Council MR/L008408/1
6 · The paper itself

Abstract

Prokaryotes have engineered sophisticated surface nanomachines that have allowed them to colonize Earth and thrive even in extreme environments. Filamentous machineries composed of type IV pilins, which are associated with an amazing array of properties ranging from motility to electric conductance, are arguably the most widespread since distinctive proteins dedicated to their biogenesis are found in most known species of prokaryotes. Several decades of investigations, starting with type IV pili and then a variety of related systems both in bacteria and archaea, have outlined common molecular and structural bases for these nanomachines. Using type IV pili as a paradigm, we will highlight in this review common aspects and key biological differences of this group of filamentous structures.

Indexed as

ArchaeaBacteriaFimbriae, BacterialFimbriae ProteinsProtein FoldingProtein Structure, TertiaryFimbriae Proteinsarchaellumclass III signal peptideprepilin peptidasetype II secretion systemtype IV pilus

Identifiers

PMID25793961
PMCPMC4471445

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.