ArticlePloS one2015
Contrast-enhanced harmonic endoscopic ultrasound-guided fine-needle aspiration in the diagnosis of solid pancreatic lesions: a retrospective study.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03525847 (The Added Value of Contrast Enhancement for Guiding EUS-FNA in Solid Pancreatic Masses), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Added Value of Contrast Enhancement for Guiding EUS-FNA in Solid Pancreatic Masses
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Imaging modalities for characterising focal pancreatic lesions.The Cochrane database of systematic reviews · 2017Pooled it
- Contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) MASTER: A novel deep learning-based system in pancreatic mass diagnosis.Cancer medicine · 2023Trial
- Proportion of unresectable pancreatic cancer specimens obtained by endoscopic ultrasound-guided tissue acquisition meeting the OncoGuide™ NCC Oncopanel System analysis suitability criteria: a single-arm, phase II clinical trial.Journal of gastroenterology · 2022Trial
- Pancreatic Adenocarcinoma: Diagnosis by Ultrasound-Guided Fine-Needle Aspiration-Cyto-Histological Correlation and Experience at a Multidisciplinary Tertiary Reference Center.Diagnostic cytopathology · 2026Observational
- Comparison of standardWorld journal of methodology · 2025Article
- Interventional Endoscopic Ultrasonography: Advances in Application.Journal of clinical medicine · 2025Review
- Updated techniques and evidence for endoscopic ultrasound-guided tissue acquisition from solid pancreatic lesions.DEN open · 2025Review
- Contrast-enhanced guided endoscopic ultrasound procedures.World journal of gastroenterology · 2024Review
- Basic Principles and Role of Endoscopic Ultrasound in Diagnosis and Differentiation of Pancreatic Cancer from Other Pancreatic Lesions: A Comprehensive Review of Endoscopic Ultrasound for Pancreatic Cancer.Journal of clinical medicine · 2024Review
- Review
- Cutting edge of endoscopic ultrasound-guided fine-needle aspiration for solid pancreatic lesions.Journal of medical ultrasonics (2001) · 2024Review
- Protocol for a Multi-Center Confirmatory Trial to Evaluate the Differential Diagnostic Performance of Contrast-Enhanced Ultrasonography Using Perflubutane in Patients with a Pancreatic Mass: A Multicenter Prospective Study.Diagnostics (Basel, Switzerland) · 2024Article
- Artificial Intelligence in Endoscopic Ultrasonography-Guided Fine-Needle Aspiration/Biopsy (EUS-FNA/B) for Solid Pancreatic Lesions: Opportunities and Challenges.Diagnostics (Basel, Switzerland) · 2023Review
- A review of contrast-enhanced harmonic endoscopic ultrasonography for pancreatic solid tumors.Journal of medical ultrasonics (2001) · 2023Review
- Contrast-Enhanced Harmonic Endoscopic Ultrasound-Guided Puncture for the Patients with Pancreatic Masses.Diagnostics (Basel, Switzerland) · 2023Review
- Advanced EUS Imaging Techniques.Digestive diseases and sciences · 2022Review
- The Utility of Endoscopic-Ultrasonography-Guided Tissue Acquisition for Solid Pancreatic Lesions.Diagnostics (Basel, Switzerland) · 2022Review
- Efficacy of EUS-guided FNB using a Franseen needle for tissue acquisition and microsatellite instability evaluation in unresectable pancreatic lesions.BMC cancer · 2020Article
- Endoscopic Ultrasound-Guided Fine-Needle Aspiration (EUS-FNA) with Image Enhancement.Diagnostics (Basel, Switzerland) · 2020Review
- Contrast-Enhanced Harmonic Endoscopic Ultrasound-Guided Fine-Needle Aspiration versus Standard Fine-Needle Aspiration in Pancreatic Masses: A Propensity Score Analysis.Diagnostics (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe negative predictive value of endoscopic ultrasonography-guided fine needle aspiration for the diagnosis of solid pancreatic lesions remains low, and the biopsy specimens are sometimes inadequate for appropriate pathological diagnosis.
aimsTo evaluate the usefulness of a novel method of contrast-enhanced harmonic endoscopic ultrasonography-guided fine-needle aspiration for the differential diagnosis and adequate sampling of solid pancreatic lesions.
methodsPatients with a diagnosis of solid pancreatic lesions who underwent fine-needle aspiration guided by contrast-enhanced harmonic endoscopic ultrasonography or by endoscopic ultrasonography from October 2010 to July 2013 were retrospectively identified and classified into the CH-EUS or EUS group, respectively. Surgical pathology and/or follow-up results were defined as the final diagnosis. Operating characteristics and adequacy of biopsy specimens by fine-needle aspiration were compared between the two groups.
resultsOperating characteristics for contrast-enhanced harmonic endoscopic ultrasonography-guided fine-needle aspiration in solid pancreatic lesions were as follows: area under the curve = 0.908, sensitivity = 81.6%, specificity = 100%, positive predictive value = 100%, negative predictive value = 74.1%, and accuracy = 87.9%. The percentage of adequate biopsy specimens in the CH-EUS group (96.6%) was greater than that in the EUS group (86.7%).
conclusionSimultaneous contrast-enhanced harmonic endoscopic ultrasonography during fine-needle aspiration is useful for improving the diagnostic yield and adequate sampling of solid pancreatic lesions.
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