Evidence map›Paper›PMID 25793551›Full record

ReviewEnvironmental health perspectives2015

Epidemiology and Ecology of Opportunistic Premise Plumbing Pathogens: Legionella pneumophila, Mycobacterium avium, and Pseudomonas aeruginosa.

Joseph O Falkinham, Elizabeth D Hilborn, Matthew J Arduino, Amy Pruden, Marc A Edwards

Abstract readReview
In one paragraph

Review in Environmental health perspectives, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Flushing as a Control Measure forEnvironmental science & technology · 2026
    Article
  9. Long-term control ofFrontiers in oral health · 2026
    Article
  10. Article
  11. Variable inhibition of differentApplied and environmental microbiology · 2025
    Article
  12. The Global Outbreak ofPathogens (Basel, Switzerland) · 2025
    Article
  13. Observational
  14. Review
  15. Article
  16. Article
  17. The State-of-the-Art ofHealthcare (Basel, Switzerland) · 2024
    Review
  18. Article
  19. Quantitative Microbial Risk Assessment of Antibiotic-ResistantEnvironmental science & technology · 2024
    Article
  20. Article

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Joseph O FalkinhamDepartment of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA.
Elizabeth D Hilborn
Matthew J Arduino
Amy Pruden
Marc A Edwards

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLegionella pneumophila, Mycobacterium avium, and Pseudomonas aeruginosa are opportunistic premise plumbing pathogens (OPPPs) that persist and grow in household plumbing, habitats they share with humans. Infections caused by these OPPPs involve individuals with preexisting risk factors and frequently require hospitalization.

objectivesThe objectives of this report are to alert professionals of the impact of OPPPs, the fact that 30% of the population may be exposed to OPPPs, and the need to develop means to reduce OPPP exposure. We herein present a review of the epidemiology and ecology of these three bacterial OPPPs, specifically to identify common and unique features.

methodsA Water Research Foundation-sponsored workshop gathered experts from across the United States to review the characteristics of OPPPs, identify problems, and develop a list of research priorities to address critical knowledge gaps with respect to increasing OPPP-associated disease. DISCUSSION: OPPPs share the common characteristics of disinfectant resistance and growth in biofilms in water distribution systems or premise plumbing. Thus, they share a number of habitats with humans (e.g., showers) that can lead to exposure and infection. The frequency of OPPP-infected individuals is rising and will likely continue to rise as the number of at-risk individuals is increasing. Improved reporting of OPPP disease and increased understanding of the genetic, physiologic, and structural characteristics governing the persistence and growth of OPPPs in drinking water distribution systems and premise plumbing is needed.

conclusionsBecause broadly effective community-level engineering interventions for the control of OPPPs have yet to be identified, and because the number of at-risk individuals will continue to rise, it is likely that OPPP-related infections will continue to increase. However, it is possible that individuals can take measures (e.g., raise hot water heater temperatures and filter water) to reduce home exposures.

Indexed as

Water SupplyHousingHumansLegionella pneumophilaLegionnaires' DiseaseMycobacterium aviumPseudomonas aeruginosaPseudomonas InfectionsTuberculosis

Identifiers

PMID25793551
PMCPMC4529011

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.