Evidence map›Paper›PMID 25793283›Full record

ArticlePloS one2015

Intimacy versus isolation: a qualitative study of sexual practices among sexually active HIV-infected patients in HIV care in Brazil, Thailand, and Zambia.

Elizabeth F Closson, Matthew J Mimiaga, Susan G Sherman, Arunrat Tangmunkongvorakul, Ruth K Friedman, Mohammed Limbada, Ayana T Moore, Kriengkrai Srithanaviboonchai, Carla A Alves, Sarah Roberts and 5 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Sexual and reproductive health and human rights of women living with HIV.Journal of the International AIDS Society · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 4 countries.

Elizabeth F ClossonThe Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America.
Matthew J MimiagaThe Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America; Harvard Medical School/Massachusetts General Hospital, Boston, Massachusetts, United States of America; Harvard School of Public Health, Boston, Massachusetts, United States of America.
Susan G ShermanJohns Hopkins School of Public Health, Baltimore, Maryland, United States of America.
Arunrat TangmunkongvorakulResearch Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Ruth K FriedmanInstituto de Pesquisa Clinica Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil.
Mohammed LimbadaCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Ayana T MooreFHI360, Durham, North Carolina, United States of America.
Kriengkrai SrithanaviboonchaiResearch Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Carla A AlvesInstituto de Pesquisa Clinica Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil.
Sarah RobertsCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Catherine E OldenburgThe Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America; Harvard School of Public Health, Boston, Massachusetts, United States of America.
Vanessa ElharrarNational Institute of Allergy and Infectious Disease, Bethesda, Maryland, United States of America.
Kenneth H MayerThe Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America; Harvard School of Public Health, Boston, Massachusetts, United States of America; Harvard Medical School/Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.
Steven A SafrenThe Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America; Harvard Medical School/Massachusetts General Hospital, Boston, Massachusetts, United States of America.
HPTN063 study team
Fenway Health · USCentre for Infectious Disease Research in Zambia · ZMChiang Mai University · THFundação Oswaldo Cruz · BRFamily Health International 360 · USHarvard University · USJohns Hopkins University · USMassachusetts General Hospital · USNational Institute of Allergy and Infectious Diseases · US

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI Sinead Delany-Moretlwe, RAPHAEL J LANDOVITZ · 2011 to 2026
$779.5M
SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
Harvard Medical School Vaccine Clinical Trials UnitUM1AI069412 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Lindsey Robert Baden, Daniel R. Kuritzkes · 2012 to 2026
$57.2M
The FIOCRUZ Therapeutic and Prevention HIV/AIDS Clinical Trials Unit (FioTrials)UM1AI069476 · NIAID · FUNDACAO OSWALDO CRUZ · PI BEATRIZ GRINSZTEJN · 2012 to 2026
$26.3M
HIV and Other Infectious Consequences of Substance UseT32DA013911 · NIDA · MIRIAM HOSPITAL · PI TRACI C GREEN, JOSIAH D RICH · 2001 to 2026
$9.6M
Harvard Medical School Vaccine Clinical Trials UnitU01AI069412 · NIAID · HARVARD MEDICAL SCHOOL · PI DOLIN, RAPHAEL · 2007 to 2011
$5.4M
Epidemiology of Infectious Diseases and BiodefenseT32AI007535 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI GRAD, YONATAN H, MURRAY, MEGAN B · 1998 to 2025
$4.8M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
NIAID NIH HHS T32 AI007535NIAID NIH HHS T32AI007535NIAID NIH HHS U01 AI069412NIAID NIH HHS UM1 AI068613NIAID NIH HHS UM1 AI068617NIAID NIH HHS UM1 AI068619NIAID NIH HHS UM1 AI069412NIAID NIH HHS UM1 AI069476NIDA NIH HHS T32 DA013911NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

The success of global treatment as prevention (TasP) efforts for individuals living with HIV/AIDS (PLWHA) is dependent on successful implementation, and therefore the appropriate contribution of social and behavioral science to these efforts. Understanding the psychosocial context of condomless sex among PLWHA could shed light on effective points of intervention. HPTN 063 was an observational mixed-methods study of sexually active, in-care PLWHA in Thailand, Zambia, and Brazil as a foundation for integrating secondary HIV prevention into HIV treatment. From 2010-2012, 80 qualitative interviews were conducted with PLWHA receiving HIV care and reported recent sexual risk. Thirty men who have sex with women (MSW) and 30 women who have sex with men (WSM) participated in equal numbers across the sites. Thailand and Brazil also enrolled 20 biologically-born men who have sex with men (MSM). Part of the interview focused on the impact of HIV on sexual practices and relationships. Interviews were recorded, transcribed, translated into English and examined using qualitative descriptive analysis. The mean age was 25 (SD = 3.2). There were numerous similarities in experiences and attitudes between MSM, MSW and WSM across the three settings. Participants had a high degree of HIV transmission risk awareness and practiced some protective sexual behaviors such as reduced sexual activity, increased use of condoms, and external ejaculation. Themes related to risk behavior can be categorized according to struggles for intimacy and fears of isolation, including: fear of infecting a sex partner, guilt about sex, sexual communication difficulty, HIV-stigma, and worry about sexual partnerships. Emphasizing sexual health, intimacy and protective practices as components of nonjudgmental sex-positive secondary HIV prevention interventions is recommended. For in-care PLWHA, this approach has the potential to support TasP. The overlap of themes across groups and countries indicates that similar intervention content may be effective for a range of settings.

Indexed as

Delivery of Health CareSexual BehaviorAdultBrazilCondomsFemaleHIV InfectionsHumansMalePublic Health SurveillanceQualitative ResearchRisk FactorsSexual PartnersSurveys and QuestionnairesThailandYoung Adult

Identifiers

PMID25793283
PMCPMC4368566
OpenAlexW2004586376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.