Evidence map›Paper›PMID 25792843›Full record

ArticleOncoTargets and therapy2015

Transcatheter arterial chemoembolization with gemcitabine and oxaliplatin for the treatment of advanced biliary tract cancer.

Qing Zhao, Sheng Qian, Liang Zhu, Xu-Dong Qu, Wei Zhang, Zhi-Ping Yan, Jie-Min Cheng, Qing-Xin Liu, Rong Liu, Jian-Hua Wang

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Radiological Loco-Regional Treatments for Cholangiocarcinoma: A Systematic Review of the Literature.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Pooled it
  2. New perspectives in biliary tract cancers.ESMO gastrointestinal oncology · 2024
    Review
  3. Article
  4. Multimodality Management of Localized Biliary Cancer.Current treatment options in oncology · 2019
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Qing ZhaoDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Sheng QianDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Liang ZhuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Xu-Dong QuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Wei ZhangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Zhi-Ping YanDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Jie-Min ChengDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Qing-Xin LiuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Rong LiuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Jian-Hua WangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Fudan University · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to determine the therapeutic efficacy and safety of transarterial chemoembolization (TACE) with gemcitabine and oxaliplatin in patients with advanced biliary tract cancer (BTC).

methodsWe retrospectively analyzed the outcomes for 65 patients with advanced BTC treated by TACE with gemcitabine 1,000 mg/m(2) and oxaliplatin 100 mg/m(2). Follow-up laboratory tests and computed tomography or magnetic resonance imaging were performed routinely to evaluate the response of the tumor to treatment. All patients were assessed for adverse effects.

resultsOf the 65 patients, 19 (29.2%) achieved a partial response, 36 (55.4%) showed stable disease, and ten (15.4%) showed progressive disease. The overall response rate was 29.2%. At the end of this study, five patients were still alive. The median overall survival was 12.0 months (95% confidence interval 8.5-15.5). There were no serious complications after TACE.

conclusionThe disease control rate and overall survival in this retrospective study were consistent with those in previous reports. TACE with gemcitabine and oxaliplatin was well tolerated and highly effective in patients with advanced BTC.

Indexed as

biliary tract cancergemcitabineoxaliplatintranscatheter arterial chemoembolization

Identifiers

PMID25792843
PMCPMC4360827
OpenAlexW2075842923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.