Evidence map›Paper›PMID 25792637›Full record

ArticleThe European respiratory journal2015

Suboptimal specificity of Xpert MTB/RIF among treatment-experienced patients.

John Z Metcalfe, Salome Makumbirofa, Beauty Makamure, Reggie Mutetwa, Renée A Peñaloza, Charles Sandy, Wilbert Bara, Stanley Mungofa, Philip C Hopewell, Peter Mason

Abstract readLetter
In one paragraph

Article in The European respiratory journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Xpert(®) MTB/RIF detection of rifampin resistance and time to treatment initiation in Harare, Zimbabwe.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2016
    Article
  11. Xpert MTB/RIF Results in Patients With Previous Tuberculosis: Can We Distinguish True From False Positive Results?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016
    Article
  12. Article
  13. Evaluation of XpertLung India : official organ of Indian Chest Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

John Z MetcalfeCurry International Tuberculosis Centre, Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, San Francisco, CA, USA john.metcalfe@ucsf.edu.
Salome MakumbirofaBiomedical Research and Training Institute, Harare, Zimbabwe.
Beauty MakamureBiomedical Research and Training Institute, Harare, Zimbabwe.
Reggie MutetwaBiomedical Research and Training Institute, Harare, Zimbabwe.
Renée A PeñalozaCurry International Tuberculosis Centre, Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, San Francisco, CA, USA.
Charles SandyNational Tuberculosis Control Program, Harare, Zimbabwe.
Wilbert BaraHarare City Health Department, Harare, Zimbabwe.
Stanley MungofaHarare City Health Department, Harare, Zimbabwe.
Philip C HopewellCurry International Tuberculosis Centre, Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, San Francisco, CA, USA.
Peter MasonBiomedical Research and Training Institute, Harare, Zimbabwe University of Zimbabwe College of Health Sciences, Harare, Zimbabwe.

Funding

Improving Early Identification of Drug Resistant Tuberculosis in HIV Prevalent SeK23AI094251 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI METCALFE, JOHN ZAPATA · 2011 to 2015
$625k
NIAID NIH HHS K23 AI094251PHS HHS U52/CCU900454
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Reagent Kits, DiagnosticArea Under CurveCommunicable Disease ControlFalse Positive ReactionsHumansMass ScreeningMycobacterium tuberculosisReproducibility of ResultsSensitivity and SpecificityTuberculosisTuberculosis, Multidrug-ResistantReagent Kits, Diagnostic

Identifiers

PMID25792637
PMCPMC4948946

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.