ReviewAsian journal of andrology
Sex determination in mammalian germ cells.
Review in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Endocrine-disrupting chemicals and female reproductive health: a growing concern.Nature reviews. Endocrinology · 2025Review
- Article
- Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cells.bioRxiv : the preprint server for biology · 2024Article
- Elevated sperm DNA fragmentation is correlated with an increased chromosomal aneuploidy rate of miscarried conceptus in women of advanced age undergoing fresh embryo transfer cycle.Frontiers in endocrinology · 2024Article
- Three-dimensional molecular architecture of mouse organogenesis.Nature communications · 2023Article
- Application of Single-Cell RNA Sequencing in Ovarian Development.Biomolecules · 2022Review
- Single-cell RNA sequencing of mitotic-arrested prospermatogonia with DAZL::GFP chickens and revealing unique epigenetic reprogramming of chickens.Journal of animal science and biotechnology · 2022Article
- Eicosanoid Biosynthesis in Male Reproductive Development: Effects of Perinatal Exposure to NSAIDs and Analgesic Drugs.Frontiers in toxicology · 2022Review
- Meiosis initiation: a story of two sexes in all creatures great and small.The Biochemical journal · 2021Review
- Identification of SRY-box 30 as an age-related essential gatekeeper for male germ-cell meiosis and differentiation.Aging cell · 2021Article
- Advances in Female Germ Cell Induction from Pluripotent Stem Cells.Stem cells international · 2021Review
- Meiotic gene activation in somatic and germ cell tumours.Andrology · 2019Review
- Emerging roles for nucleoporins in reproductive cellular physiologyCanadian journal of physiology and pharmacology · 2019Review
- Delayed male germ cell sex-specification permits transition into embryonal carcinoma cells with features of primed pluripotency.Development (Cambridge, England) · 2018Article
- Bone morphogenetic protein and retinoic acid synergistically specify female germ-cell fate in mice.The EMBO journal · 2017Article
- Article
- Environmental influences on ovarian dysgenesis - developmental windows sensitive to chemical exposures.Nature reviews. Endocrinology · 2017Review
- Meiotic onset is reliant on spatial distribution but independent of germ cell number in the mouse ovary.Journal of cell science · 2016Article
- Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts.Nature communications · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Germ cells are the precursors of the sperm and oocytes and hence are critical for survival of the species. In mammals, they are specified during fetal life, migrate to the developing gonads and then undergo a critical period during which they are instructed, by the soma, to adopt the appropriate sexual fate. In a fetal ovary, germ cells enter meiosis and commit to oogenesis, whereas in a fetal testis, they avoid entry into meiosis and instead undergo mitotic arrest and mature toward spermatogenesis. Here, we discuss what we know so far about the regulation of sex-specific differentiation of germ cells, considering extrinsic molecular cues produced by somatic cells, as well as critical intrinsic changes within the germ cells. This review focuses almost exclusively on our understanding of these events in the mouse model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.