Evidence map›Paper›PMID 25791202›Full record

ArticleClinical radiology2015

Technical assessment of whole body angiography and cardiac function within a single MRI examination.

S J Gandy, M Lambert, J J F Belch, I D Cavin, E Crowe, R Littleford, J A Macfarlane, S Z Matthew, P Martin, R S Nicholas and 6 more

Open access · hybridAbstract readEvaluation Study
In one paragraph

Article in Clinical radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
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  4. Systemic arteriosclerosis is associated with left ventricular remodeling but not atherosclerosis: a TASCFORCE study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

S J GandyNHS Tayside Clinical Radiology, Ninewells Hospital, Dundee DD1 9SY, UK; NHS Tayside Medical Physics, Ninewells Hospital, Dundee DD1 9SY, UK. Electronic address: Stephen.Gandy@nhs.net.
M LambertMedical Research Institute, College of Medicine, University of Dundee, Dundee DD1 9SY, UK.
J J F BelchMedical Research Institute, College of Medicine, University of Dundee, Dundee DD1 9SY, UK.
I D CavinNHS Tayside Medical Physics, Ninewells Hospital, Dundee DD1 9SY, UK.
E CroweNHS Tayside Clinical Radiology, Ninewells Hospital, Dundee DD1 9SY, UK.
R LittlefordMedical Research Institute, College of Medicine, University of Dundee, Dundee DD1 9SY, UK.
J A MacfarlaneNHS Tayside Medical Physics, Ninewells Hospital, Dundee DD1 9SY, UK.
S Z MatthewMedical Research Institute, College of Medicine, University of Dundee, Dundee DD1 9SY, UK.
P MartinNHS Tayside Clinical Radiology, Ninewells Hospital, Dundee DD1 9SY, UK.
R S NicholasNHS Tayside Clinical Radiology, Ninewells Hospital, Dundee DD1 9SY, UK; NHS Tayside Medical Physics, Ninewells Hospital, Dundee DD1 9SY, UK.
A D StruthersMedical Research Institute, College of Medicine, University of Dundee, Dundee DD1 9SY, UK.
F SullivanDepartment of Family and Community Medicine, University of Toronto, Toronto, Canada; Department of Research and Innovation, North York General Hospital, Toronto, Canada.
S A WaughNHS Tayside Medical Physics, Ninewells Hospital, Dundee DD1 9SY, UK.
R D WhiteNHS Tayside Clinical Radiology, Ninewells Hospital, Dundee DD1 9SY, UK; Department of Clinical Radiology, University Hospital of Wales, Cardiff CF14 4XW, UK.
J R Weir-McCallMedical Research Institute, College of Medicine, University of Dundee, Dundee DD1 9SY, UK.
J G HoustonNHS Tayside Clinical Radiology, Ninewells Hospital, Dundee DD1 9SY, UK; Medical Research Institute, College of Medicine, University of Dundee, Dundee DD1 9SY, UK.
University of Dundee · GBNinewells Hospital · GBNHS Tayside · GB

Funding

Wellcome Trust WT 085664
6 · The paper itself

Abstract

aimTo evaluate a combined protocol for simultaneous cardiac MRI (CMR) and contrast-enhanced (CE) whole-body MR angiography (WB-MRA) techniques within a single examination. MATERIALS AND

methodsAsymptomatic volunteers (n = 48) with low-moderate risk of cardiovascular disease (CVD) were recruited. The protocol was divided into four sections: (1) CMR of left ventricle (LV) structure and function; (2) CE-MRA of the head, neck, and thorax followed by the distal lower limbs; (3) CMR LV "late gadolinium enhancement" assessment; and (4) CE-MRA of the abdomen and pelvis followed by the proximal lower limbs. Multiple observers undertook the image analysis.

resultsFor CMR, the mean ejection fraction (EF) was 67.3 ± 4.8% and mean left ventricular mass (LVM) was 100.3 ± 22.8 g. The intra-observer repeatability for EF ranged from 2.1-4.7% and from 9-12 g for LVM. Interobserver repeatability was 8.1% for EF and 19.1 g for LVM. No LV delayed myocardial enhancement was observed. For WB-MRA, some degree of luminal narrowing or stenosis was seen at 3.6% of the vessel segments (involving n = 29 of 48 volunteers) and interobserver radiological opinion was consistent in 96.7% of 1488 vessel segments assessed.

conclusionCombined assessment of WB-MRA and CMR can be undertaken within a single examination on a clinical MRI system. The associated analysis techniques are repeatable and may be suitable for larger-scale cardiovascular MRI studies.

Indexed as

AdultAgedArterial Occlusive DiseasesCardiac-Gated Imaging TechniquesCardiovascular DiseasesCoronary StenosisFeasibility StudiesFemaleHealthy VolunteersHeartHumansMagnetic Resonance AngiographyMagnetic Resonance Imaging, CineMaleMiddle AgedObserver Variation

Identifiers

PMID25791202
PMCPMC4728185
OpenAlexW1993085266

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.