Evidence map›Paper›PMID 25790903›Full record

Trial reportSchizophrenia research2015

UPSA-M: Feasibility and initial validity of a mobile application of the UCSD Performance-Based Skills Assessment.

Raeanne C Moore, Pariya L Fazeli, Thomas L Patterson, Colin A Depp, David J Moore, Eric Granholm, Dilip V Jeste, Brent T Mausbach

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Schizophrenia research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Overview of measurement-based positive psychiatry.Nordic journal of psychiatry · 2018
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Raeanne C MooreDepartment of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA; The Sam and Rose Stein Institute for Research on Aging, University of California San Diego, La Jolla, CA, 92093, USA. Electronic address: r6moore@ucsd.edu.
Pariya L FazeliDepartment of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA. Electronic address: pfazeli@ucsd.edu.
Thomas L PattersonDepartment of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA. Electronic address: tpatterson@ucsd.edu.
Colin A DeppDepartment of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA; The Sam and Rose Stein Institute for Research on Aging, University of California San Diego, La Jolla, CA, 92093, USA; VA San Diego Healthcare System, San Diego, CA, 92161, USA. Electronic address: cdepp@ucsd.edu.
David J MooreDepartment of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA. Electronic address: djmoore@ucsd.edu.
Eric GranholmDepartment of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA; VA San Diego Healthcare System, San Diego, CA, 92161, USA. Electronic address: egranholm@ucsd.edu.
Dilip V JesteDepartment of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA; The Sam and Rose Stein Institute for Research on Aging, University of California San Diego, La Jolla, CA, 92093, USA. Electronic address: djeste@ucsd.edu.
Brent T MausbachDepartment of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA. Electronic address: bmausbach@ucsd.edu.

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello · 2001 to 2026
$50.4M
FELLOWSHIP IN GERIATRIC MENTAL HEALTHT32MH019934 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elizabeth W Twamley · 1994 to 2026
$9.5M
Interdisciplinary Research Fellowship in NeuroAIDSR25MH081482 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MARIANA CHERNER · 2007 to 2026
$5.2M
Skills Training and Empowerment Program for Middle-Aged and Older Patients with PR01MH084967 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MAUSBACH, BRENT T · 2009 to 2013
$2.8M
A Novel Neurorehabilitation Approach for Cognitive Aging with HIVK99AG048762 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WHEELER, PARIYA FAZELI · 2014 to 2015
$226k
NIA NIH HHS K99 AG048762NIA NIH HHS L30 AG045921NIMH NIH HHS L30 MH104725NIMH NIH HHS MH084967NIMH NIH HHS P30 MH062512NIMH NIH HHS R01 MH084967NIMH NIH HHS R25 MH081482NIMH NIH HHS T32 MH019934
6 · The paper itself

Abstract

objectiveThis study aimed to develop and validate a tablet mobile application version of the UCSD Performance-Based Skills Assessment (UPSA-M), a widely used test for assessing functional capacity in schizophrenia and other neurocognitively impaired patient populations.

methodsThe UPSA-M was developed for an iPad platform. Twenty-one middle-aged and older adults with schizophrenia and 13 healthy comparison (HC) participants completed a brief iPad tutorial, followed by the UPSA-M (full version, which includes all components of Brief UPSA-M) and a computer usage questionnaire. During a separate visit, patients with schizophrenia and HC participants completed the Brief UPSA (UPSA-B), and patients with schizophrenia completed a symptom inventory and brief neuropsychological screening battery.

resultsThe UPSA-M was feasible for use among middle aged and older adults with schizophrenia with no prior history of tablet usage. The UPSA-M was able to differentiate between schizophrenia and HC participants 80% of the time, and this differential ability increased to 87% with the UPSA-M Brief. Traditional UPSA scores, UPSA-B scores, and neuropsychological performance were related to UPSA-M scores, whereas symptoms of psychopathology, experience with tablet technology, or difficulties operating the device were not significantly associated with UPSA-M.

conclusionsThe UPSA-M performed just as well as the standard-of-practice version. These preliminary results indicate that the UPSA-M Brief has greater sensitivity than the full version of the UPSA-M, and carries the advantage of a shorter administration time. Overall, the UPSA-M appears to be a promising mobile tool to assess functional capacity.

Indexed as

Mobile ApplicationsSchizophrenic PsychologyActivities of Daily LivingAdultAgedCognition DisordersFemaleHumansMaleMiddle AgedNeuropsychological TestsPsychiatric Status Rating ScalesPsychomotor PerformanceReproducibility of ResultsROC CurveSchizophrenia

Identifiers

PMID25790903
PMCPMC4409538

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.