ReviewCurrent hypertension reports2015
Blood pressure variability: assessment, predictive value, and potential as a therapeutic target.
Review in Current hypertension reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
90 citing papers in PubMed, 4 syntheses or guidelines pooled it, 208 citations in OpenAlex.
- Patient-Specific Factors Predicting Renal Denervation Response in Patients With Hypertension: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2024Pooled it
- Non-invasive parameters of autonomic function using beat-to-beat cardiovascular variations and arterial stiffness in hypertensive individuals: a systematic review.Biomedical engineering online · 2024Pooled it
- Association between mental illness and blood pressure variability: a systematic review.Biomedical engineering online · 2022Pooled it
- 24-Hour Blood Pressure Variability Assessed by Average Real Variability: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2017Pooled it
- Effects of long-term almond consumption on markers for vascular function and cardiometabolic risk in men and women with prediabetes: results of a randomized, controlled cross-over trial.European journal of nutrition · 2024Trial
- Visit-to-Visit Office Blood Pressure Variability and Cardiovascular Outcomes in SPRINT (Systolic Blood Pressure Intervention Trial).Hypertension (Dallas, Tex. : 1979) · 2017Trial
- Machine learning-driven integration of 24-hour ambulatory blood pressure and its variability.PLOS digital health · 2026Article
- Individuals with posttraumatic stress disorder have increased beat-to-beat blood pressure variability.American journal of physiology. Regulatory, integrative and comparative physiology · 2026Article
- The Impact of Short-Term Blood Pressure Variability on All-Cause Mortality in Patients With Acute Myocardial Infarction.Cardiology research and practice · 2026Article
- High intradialysis diastolic blood pressure variability is an independent predictor of all-cause mortality.Annals of medicine · 2025Article
- Association of 24-Hour blood pressure average real variability with poor prognosis in critically ill patients with coronary artery disease.Scientific reports · 2025Article
- Blood pressure variability: a review.Journal of hypertension · 2025Review
- Mediation of Time-Related Blood Pressure Variability on Intensive Blood Pressure Lowering and Functional Outcomes Post Endovascular Therapy: A Post Hoc Analysis of the OPTIMAL-BP Trial.Journal of the American Heart Association · 2025Article
- High blood pressure inhibits cardiovascular responsiveness to expressive classical music.Scientific reports · 2025Article
- The correlation between age, blood pressure variability and estimated pulse wave velocity.Scientific reports · 2025Article
- Article
- Blood pressure reactivity to mental stress is related to daily blood pressure variability in postmenopausal hypertensive women.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Article
- Blood pressure variability associated with falls in nursing home residents.Geriatrics & gerontology international · 2024Article
- Beat-to-Beat Blood Pressure Variability Within 24 Hours of Ischemic Stroke Onset: A Potential Predictor of Functional Prognosis.Journal of the American Heart Association · 2024Article
- Relationship between visit-to-visit blood pressure variability and depressive mood in Korean primary care patients.BMC primary care · 2024Article
30 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A large body of evidence has consistently supported the relationship between blood pressure (BP) levels and the risk of cardiovascular complications. In recent years, several independent studies have also indicated that this risk may not only depend on the magnitude of the blood pressure elevation per se but also on the presence of other associated conditions such as increased blood pressure variability. This concept has been supported by a series of reports, most of which post hoc analyses of clinical trials in hypertension, showing that increasing values of BP variability (BPV) (either in the short term, in the midterm, or in the long term) may predict development, progression, and severity of cardiac, vascular, and renal organ damage, as well as cardiovascular events and mortality. Remarkably, studies conducted in populations at high cardiovascular risk have shown increasing values of BPV in the individual subjects (so-called intra- or within-individual BPV) to be strong predictors of cardiovascular morbidity and mortality, even to a larger extent than average BP values. However, in subjects at low to moderate cardiovascular risk, the contribution of BPV to cardiovascular risk prediction over and beyond average BP values has been shown to be only moderate. The aim of this paper is to critically review the evidence addressing the prognostic relevance of different components of BPV addressing a yet open question, i.e., whether routine assessment of BPV in clinical practice should be regarded as an additional target of antihypertensive treatment to improve cardiovascular protection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.