ArticleThe Journal of heart valve disease2014
Effect of mitral annuloplasty device shape and size on leaflet and myofiber stress following repair of posterior leaflet prolapse: a patient-specific finite element simulation.
Article in The Journal of heart valve disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Surgical as Opposed to Transcatheter Aortic Valve Replacement Improves Basal Interventricular Septal Hypertrophy.Circulation journal : official journal of the Japanese Circulation Society · 2018Trial
- Mitral Valve Prolapse: A Disease of Valve and Ventricle.Journal of the American College of Cardiology · 2018Article
- Finite Element Modeling of Mitral Valve Repair.Journal of biomechanical engineering · 2016Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
background and aim of the studyMitral annuloplasty (MA) devices are available in different shapes and sizes, but the preferred shape and size are unclear.
methodsA previously described and validated finite element (FE) model of the left ventricle (LV) with mitral valve (MV) based on magnetic resonance imaging and three-dimensional echocardiography images from a patient with posterior leaflet (PL; P2) prolapse was used in this study. FE models of MA devices with different shapes (flat partial, shallow saddle, pronounced saddle) and sizes (36-30) were created. Virtual leaflet resection + MA with each shape and size were simulated. Leaflet geometry, stresses in the leaflets and base of the LV, and forces in the chordae and MA sutures were calculated.
resultsAll MA shapes increased the mitral coaptation length, reduced the elevated PL stress at end-diastole (ED) and end-systole (ES) that occurred after leaflet resection, and reduced anterior leaflet (AL) stress at ES. MA devices of all shapes and sizes modestly reduced myofiber stress at the LV base in ED and ES. In general, saddle-shaped devices had the greatest effect.
conclusionAll MA shapes increased coaptation length and reduced mitral leaflet stress and myofiber stress in the base of the LV. an additional reduction in MA size further increased coaptation length and reduced leaflet and myofiber stress. In general, saddle-shaped devices had the greatest effect.
Indexed as
Identifiers
25790620PMC6040586W79342690What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.