Evidence map›Paper›PMID 25790305›Full record

ArticlePloS one2015

Surveillance and clinical characterization of influenza in a university cohort in Singapore.

Aidan Lyanzhiang Tan, Ramandeep Kaur Virk, Paul Anantharajah Tambyah, Masafumi Inoue, Elizabeth Ai-Sim Lim, Ka-Wei Chan, C Senthamarai Chelvi, Say-Tat Ooi, Catherine Chua, Boon-Huan Tan

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Aidan Lyanzhiang TanDepartment of Medicine, National University of Singapore, Singapore, Singapore.
Ramandeep Kaur VirkDepartment of Medicine, National University of Singapore, Singapore, Singapore.
Paul Anantharajah TambyahDepartment of Medicine, National University of Singapore, Singapore, Singapore.
Masafumi InoueAgency for Science, Technology and Research, Singapore, Singapore.
Elizabeth Ai-Sim LimDetection & Diagnostics Laboratory, DSO National Laboratories, Singapore, Singapore.
Ka-Wei ChanDetection & Diagnostics Laboratory, DSO National Laboratories, Singapore, Singapore.
C Senthamarai ChelviDepartment of Medicine, National University of Singapore, Singapore, Singapore.
Say-Tat OoiDepartment of General Medicine, Khoo Teck Puat Hospital, Singapore, Singapore.
Catherine ChuaUniversity Health Centre, National University of Singapore, Singapore, Singapore.
Boon-Huan TanDetection & Diagnostics Laboratory, DSO National Laboratories, Singapore, Singapore; Department of Epidemiology and Public Health, National University of Singapore, Singapore, Singapore.
National University of Singapore · SGDSO National Laboratories · SGAgency for Science, Technology and Research · SGKhoo Teck Puat Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSoutheast Asia is a potential locus for the emergence of novel influenza strains. However, information on influenza within the region is limited.

objectivesThis study was to determine the proportion of influenza-like illness (ILI) caused by influenza A and B viruses in a university cohort in Singapore, identify important distinctive clinical features of influenza infection and potential factors associated with influenza infection compared with other causes of ILI. METHODOLOGY: A surveillance study was conducted from 2007 to 2009, at the University Health and Wellness Centre, National University of Singapore (NUS). Basic demographic information and nasopharyngeal swabs were collected from consenting students and staff with ILI, with Influenza A and B identified by both culture and molecular methods.

resultsProportions of influenza A and B virus infections in subjects with ILI were 153/500 (30.6%) and 11/500 (2.2%) respectively. The predominant subtype was A/H1N1, including both the seasonal strain (20/153) and the pandemic strain (72/153). The clinical symptom of fever was more common in subjects with laboratory confirmed influenza than other ILIs. On-campus hostel residence and being a student (compared with staff) were associated with increased risk of laboratory confirmed influenza A/H1N1 2009 infection.

conclusionsThis study provides a baseline prevalence of influenza infection within young adults in Singapore in a university setting. Potential risk factors, such as hostel residence, were identified, allowing for more targeted infection control measures in the event of a future influenza pandemic.

Indexed as

AdultCohort StudiesDemographyFemaleHumansInfluenza A Virus, H1N1 SubtypeInfluenza B virusInfluenza, HumanMaleNasopharynxOdds RatioReverse Transcriptase Polymerase Chain ReactionRisk FactorsRNA, ViralSingaporeUniversitiesRNA, Viral

Identifiers

PMID25790305
PMCPMC4366074
OpenAlexW2036384381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.