Evidence map›Paper›PMID 25790223›Full record

ReviewPLoS pathogens2015

To be or not IIb: a multi-step process for Epstein-Barr virus latency establishment and consequences for B cell tumorigenesis.

Alexander M Price, Micah A Luftig

Open access · goldAbstract readReview
In one paragraph

Review in PLoS pathogens, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

123 citing papers in PubMed, 170 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. A tonsil organoid model reveals Epstein-Barr virus-infected germinal center B cell states during primary infection.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Increased Frequency of the Chemokine Receptor CCR2 on Circulating CD19+CD5+ Lymphocytes in Therapy-Naïve CLL Patients With the Detectable EBV DNA and High-Avidity Antibodies Against the EBV Capsid Antigen.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
  12. Article
  13. LANA-specific CD4Nature communications · 2025
    Article
  14. Article
  15. Article
  16. Arginine Metabolism SupportsbioRxiv : the preprint server for biology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Chromatin Control of EBV Infection and Latency.Current topics in microbiology and immunology · 2025
    Article

63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexander M PriceDepartment of Molecular Genetics and Microbiology, Duke Center for Virology, Duke University Medical Center, Durham, North Carolina, United States of America.
Micah A LuftigDepartment of Molecular Genetics and Microbiology, Duke Center for Virology, Duke University Medical Center, Durham, North Carolina, United States of America.
Duke Medical Center · US

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
Viral Oncology Training GrantT32CA009111 · NCI · DUKE UNIVERSITY · PI LUFTIG, MICAH A. · 1985 to 2023
$8.9M
Host pathways regulating Epstein-Barr virus-mediated B cell growth transformationR01CA140337 · NCI · DUKE UNIVERSITY · PI LUFTIG, MICAH ALAN · 2011 to 2025
$5.9M
Temporal regulation of the essential Epstein-Barr virus oncoprotein LMP1F31CA180451 · NCI · DUKE UNIVERSITY · PI PRICE, ALEXANDER MATTHEW · 2013 to 2015
$99k
NCI NIH HHS F31 CA180451NCI NIH HHS R01 CA140337NCI NIH HHS T32 CA009111NIAID NIH HHS 5P30 AI064518NIAID NIH HHS P30 AI064518
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

B-LymphocytesCell ProliferationCell SurvivalCell Transformation, ViralEpstein-Barr Virus InfectionsGene Expression Regulation, ViralHerpesvirus 4, HumanHumansRNA, UntranslatedRNA, ViralVirus LatencyRNA, UntranslatedRNA, Viral

Identifiers

PMID25790223
PMCPMC4366242
OpenAlexW1981006469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.