Trial reportPloS one2015
At what level of heat load are age-related impairments in the ability to dissipate heat evident in females?
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 63 citations in OpenAlex.
- Age differences in cardiac autonomic regulation during intermittent exercise in the heat.European journal of applied physiology · 2020Trial
- Defining Sex- and Age-Specific Initial Stay Times for Continuous Moderate-Intensity Work in Hot Environments Before Heat-Mitigation Controls Are Implemented - Part A.American journal of industrial medicine · 2025Article
- Defining Sex- and Age-Specific Initial Stay Times for Continuous Heavy-Intensity Work in Hot Environments Before Heat-Mitigation Controls Are Implemented-Part B.American journal of industrial medicine · 2025Article
- Rating of Perceived Exertion: A Large Cross-Sectional Study Defining Intensity Levels for Individual Physical Activity Recommendations.Sports medicine - open · 2024Article
- Biophysical, thermo-physiological and perceptual determinants of cool-seeking behaviour during exercise in younger and older women.Experimental physiology · 2024Article
- Experimental research in environmentally induced hyperthermic older persons: A systematic quantitative literature review mapping the available evidence.Temperature (Austin, Tex.) · 2024Article
- Indoor overheating: A review of vulnerabilities, causes, and strategies to prevent adverse human health outcomes during extreme heat events.Temperature (Austin, Tex.) · 2024Review
- Can exposure to heat attenuate neurodegeneration in older adults with Parkinson's disease?Frontiers in aging neuroscience · 2023Article
- Human temperature regulation under heat stress in health, disease, and injury.Physiological reviews · 2022Review
- Impact of uncomplicated controlled hypertension on thermoregulation during exercise-heat stress.Journal of human hypertension · 2021Article
- Temperature regulation during exercise in the heat: Insights for the aging athlete.Journal of science and medicine in sport · 2021Review
- Challenges arising for older workers from participating in a workplace intervention addressing work ability: a qualitative study from Germany.International archives of occupational and environmental health · 2021Article
- The Role of Environmental Conditions on Master Marathon Running Performance in 1,280,557 Finishers the 'New York City Marathon' From 1970 to 2019.Frontiers in physiology · 2021Article
- Psychrometric limits and critical evaporative coefficients for exercising older women.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Skin Temperature in Master Long-Distance Runners-Results From a Field Study at the 2018 World Master Athletics Championships.Frontiers in sports and active living · 2020Article
- Age-Related Changes in the Thermoregulatory Properties in Bank Voles From a Selection Experiment.Frontiers in physiology · 2020Article
- Individual Responses to Heat Stress: Implications for Hyperthermia and Physical Work Capacity.Frontiers in physiology · 2020Review
- Is There a Need to Integrate Human Thermal Models with Weather Forecasts to Predict Thermal Stress?International journal of environmental research and public health · 2019Review
- Towards establishing evidence-based guidelines on maximum indoor temperatures during hot weather in temperate continental climates.Temperature (Austin, Tex.) · 2019Review
- Screening criteria for increased susceptibility to heat stress during work or leisure in hot environments in healthy individuals aged 31-70 years.Temperature (Austin, Tex.) · 2018Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
Studies have reported that older females have impaired heat loss responses during work in the heat compared to young females. However, it remains unclear at what level of heat stress these differences occur. Therefore, we examined whole-body heat loss [evaporative (HE) and dry heat loss, via direct calorimetry] and changes in body heat storage (∆Hb, via direct and indirect calorimetry) in 10 young (23±4 years) and 10 older (58±5 years) females matched for body surface area and aerobic fitness (VO2peak) during three 30-min exercise bouts performed at incremental rates of metabolic heat production of 250 (Ex1), 325 (Ex2) and 400 (Ex3) W in the heat (40°C, 15% relative humidity). Exercise bouts were separated by 15 min of recovery. Since dry heat gain was similar between young and older females during exercise (p=0.52) and recovery (p=0.42), differences in whole-body heat loss were solely due to HE. Our results show that older females had a significantly lower HE at the end of Ex2 (young: 383±34 W; older: 343±39 W, p=0.04) and Ex3 (young: 437±36 W; older: 389±29 W, p=0.008), however no difference was measured at the end of Ex1 (p=0.24). Also, the magnitude of difference in the maximal level of HE achieved between the young and older females became greater with increasing heat loads (Ex1=10.2%, Ex2=11.6% and Ex3=12.4%). Furthermore, a significantly greater ∆Hb was measured for all heat loads for the older females (Ex1: 178±44 kJ; Ex2: 151±38 kJ; Ex3: 216±25 kJ, p=0.002) relative to the younger females (Ex1: 127±35 kJ; Ex2: 96±45 kJ; Ex3: 146±46 kJ). In contrast, no differences in HE or ∆Hb were observed during recovery (p>0.05). We show that older habitually active females have an impaired capacity to dissipate heat compared to young females during exercise-induced heat loads of ≥325 W when performed in the heat.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.