Evidence map›Paper›PMID 25789869›Full record

ReviewChemical reviews2015

Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.

Jessica Nasica-Labouze, Phuong H Nguyen, Fabio Sterpone, Olivia Berthoumieu, Nicolae-Viorel Buchete, Sébastien Coté, Alfonso De Simone, Andrew J Doig, Peter Faller, Angel Garcia and 14 more

Abstract readReview
In one paragraph

Review in Chemical reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 203 papers.

0numbers the graph read from it
0cells of the map it votes in
203citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

203 citing papers in PubMed.

  1. Article
  2. Phosphate- and pH-dependent self-assembly of recombinant spider silk proteins.Protein science : a publication of the Protein Society · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Modulation of AβJournal of chemical information and modeling · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Ensemble Docking for Intrinsically Disordered Proteins.Journal of chemical information and modeling · 2025
    Article
  14. Article
  15. Formation of a β-Endorphin Corona Mitigates Alzheimer's Amyloidogenesis.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  16. Article
  17. Review
  18. Ensemble docking for intrinsically disordered proteins.bioRxiv : the preprint server for biology · 2025
    Article
  19. Review
  20. Review

143 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Jessica Nasica-Labouze†Laboratoire de Biochimie Théorique, Institut de Biologie Physico-Chimique (IBPC), UPR9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, 13 rue Pierre et Marie Curie, 75005 Paris, France.
Phuong H Nguyen†Laboratoire de Biochimie Théorique, Institut de Biologie Physico-Chimique (IBPC), UPR9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, 13 rue Pierre et Marie Curie, 75005 Paris, France.
Fabio Sterpone†Laboratoire de Biochimie Théorique, Institut de Biologie Physico-Chimique (IBPC), UPR9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, 13 rue Pierre et Marie Curie, 75005 Paris, France.
Olivia Berthoumieu‡LCC (Laboratoire de Chimie de Coordination), CNRS, Université de Toulouse, Université Paul Sabatier (UPS), Institut National Polytechnique de Toulouse (INPT), 205 route de Narbonne, BP 44099, Toulouse F-31077 Cedex 4, France.
Nicolae-Viorel Buchete
Sébastien Coté∥Département de Physique and Groupe de recherche sur les protéines membranaires (GEPROM), Université de Montréal, C.P. 6128, succursale Centre-ville, Montréal, Québec H3C 3T5, Canada.
Alfonso De Simone⊥Department of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.
Andrew J Doig#Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, United Kingdom.
Peter Faller‡LCC (Laboratoire de Chimie de Coordination), CNRS, Université de Toulouse, Université Paul Sabatier (UPS), Institut National Polytechnique de Toulouse (INPT), 205 route de Narbonne, BP 44099, Toulouse F-31077 Cedex 4, France.
Angel Garcia
Alessandro Laio○The International School for Advanced Studies (SISSA), Via Bonomea 265, 34136 Trieste, Italy.
Mai Suan Li◆Institute of Physics, Polish Academy of Sciences, Al. Lotnikow 32/46, 02-668 Warsaw, Poland.
Simone Melchionna⬠Instituto Processi Chimico-Fisici, CNR-IPCF, Consiglio Nazionale delle Ricerche, 00185 Roma, Italy.
Normand Mousseau
Yuguang Mu▲School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551 Singapore.
Anant Paravastu⊕National High Magnetic Field Laboratory, 1800 East Paul Dirac Drive, Tallahassee, Florida 32310, United States.
Samuela Pasquali†Laboratoire de Biochimie Théorique, Institut de Biologie Physico-Chimique (IBPC), UPR9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, 13 rue Pierre et Marie Curie, 75005 Paris, France.
David J Rosenman
Birgit Strodel△Institute of Complex Systems: Structural Biochemistry (ICS-6), Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
Bogdan Tarus†Laboratoire de Biochimie Théorique, Institut de Biologie Physico-Chimique (IBPC), UPR9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, 13 rue Pierre et Marie Curie, 75005 Paris, France.
John H Viles▼School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, United Kingdom.
Tong Zhang†Laboratoire de Biochimie Théorique, Institut de Biologie Physico-Chimique (IBPC), UPR9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, 13 rue Pierre et Marie Curie, 75005 Paris, France.
Chunyu Wang
Philippe Derreumaux†Laboratoire de Biochimie Théorique, Institut de Biologie Physico-Chimique (IBPC), UPR9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, 13 rue Pierre et Marie Curie, 75005 Paris, France.

Funding

Solid State NMR Structural Analysis of Oligomeric Alzheimer's Beta-Amyloid PeptideR01AG045703 · NIA · GEORGIA INSTITUTE OF TECHNOLOGY · PI PARAVASTU, ANANT KRISHNA · 2014 to 2018
$1.5M
European Research Council 258748NIA NIH HHS R01 AG045703
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesComputer SimulationAmino Acid SequenceAnimalsCell MembraneHumansMolecular Sequence DataProtein MultimerizationWaterAmyloid beta-PeptidesWater

Identifiers

PMID25789869
PMCPMC5504919

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.