ArticleSao Paulo medical journal = Revista paulista de medicina
Characteristics of fetuses evaluated due to suspected anencephaly: a population-based cohort study in southern Brazil.
Article in Sao Paulo medical journal = Revista paulista de medicina. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Investigating the use of ultrasonography for the antenatal diagnosis of structural congenital anomalies in low-income and middle-income countries: a systematic review.BMJ paediatrics open · 2020Pooled it
- The prevalence of neural tube defects in eastern Ethiopia: A population-based surveillance.PLOS global public health · 2026Article
- Imaging in the presence of meroanencephaly.Radiology case reports · 2021Article
- Frederik Ruysch (1638-1731): Historical perspective and contemporary analysis of his teratological legacy.American journal of medical genetics. Part A · 2017Review
- The etiopathogenic and morphological spectrum of anencephaly: a comprehensive review of literature.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieReview
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
CONTEXT AND
objectiveAnencephaly is considered to be the most common type of neural tube defect. Our aim was to assess the clinical and gestational features of a cohort of fetuses with suspected anencephaly. DESIGN AND
settingPopulation-based retrospective cohort study in a referral hospital in southern Brazil.
methodsThe sample consisted of fetuses referred due to suspected anencephaly, to the Fetal Medicine Service of Hospital Materno Infantil Presidente Vargas, between January 2005 and September 2013. Clinical, radiological, pathological and survival data were gathered.
resultsOur sample was composed of 29 fetuses. The diagnosis of suspected anencephaly was made on average at 21.3 weeks of gestation. Seven fetuses had malformations that affected other organs, and these included oral clefts (n = 4) and congenital heart defects (n = 2). In 16 cases, there was termination of pregnancy (n = 12) or intrauterine death (n = 4). Regarding those who were born alive (n = 13), all of them died in the first week of life. After postnatal evaluation, the diagnosis of anencephaly was confirmed in 22 cases (75.9%). Other conditions included amniotic band disruption complex (6.9%), microhydranencephaly (6.9%), merocrania (3.4%) and holoprosencephaly (3.4%).
conclusionsDifferent conditions involving the cranial vault may be confused with anencephaly, as seen in our sample. However, these conditions also seem to have a poor prognosis. It seems that folic acid supplementation is not being properly performed.
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