ReviewWorld journal of clinical cases2015
Gall bladder carcinoma: Aggressive malignancy with protean loco-regional and distant spread.
Review in World journal of clinical cases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
52 citing papers in PubMed, 101 citations in OpenAlex.
- High Expression of SSEA3 and Globo H Predicts Poor Outcomes in Resected Extrahepatic Cholangiocarcinoma: A Single-Center Retrospective Cohort Study.Cancer medicine · 2026Article
- C2ORF68 stabilizes SIVA1 to upregulate BCL-2 and suppress apoptosis in gallbladder cancer.Cell death discovery · 2026Article
- Article
- Intracholecystic papillary-tubular neoplasm diagnosed by peroral cholangioscopy.Clinical journal of gastroenterology · 2026Article
- A novel model based on apparent diffusion coefficient and signal intensity on MRI to quantify subtle internal difference between tumor-adjacent and -distant liver tissues in TBMC medical imaging · 2026Article
- Carbon dots in cancer therapy: a novel approach to targeted drug delivery and reduced toxicity in gallbladder cancer.Frontiers in chemistry · 2026Review
- Isolated Metachronous Intraluminal Colonic Metastasis in Carcinoma Gall Bladder: The Path Less Trodden.ACG case reports journal · 2025Article
- Update on the Role of Imaging in the Diagnosis, Staging, and Prognostication of Gallbladder Cancer.The Indian journal of radiology & imaging · 2025Review
- Article
- Liquid biopsy in gallbladder carcinoma: Current evidence and future prospective.The journal of liquid biopsy · 2024Review
- Article
- Multifocality in gallbladder cancer: An imaging-based study.Clinical and experimental hepatology · 2024Article
- Comprehensive treatment of gallbladder cancer: a case report.Annals of medicine and surgery (2012) · 2024Article
- Review
- Utility of 18-Flurodeoxyglucose Positron Emission Tomography-Computed Tomography (World journal of nuclear medicine · 2023Article
- Temporal Trends of Stages and Survival of Biliary Tract Cancers in the United States and Associations with Demographic Factors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Article
- Prognosis and Treatment Outcomes of Bone Metastasis in Gallbladder Adenocarcinoma: A SEER-Based Study.Cancers · 2023Article
- Gastrointestinal involvement in gallbladder cancer: Computed tomography findings and proposal of a classification system.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023Article
- Anti-PD-1-based immunotherapy plus lenvatinib to treat advanced gallbladder cancer in the elderly: a case series and review of current literature.Journal of cancer research and clinical oncology · 2023Review
- Giant Gallbladder Tumor, Unusual Cancer-Case Report and Short Review of Literature.Diagnostics (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most common malignancy of biliary tract is gallbladder cancer (GBC) which is the third most common cancer in gastrointestinal tract. It is a lethal disease for most patients in spite of growing awareness and improved diagnostic techniques. GBC has a very poor prognosis and the 5 year survival rate is < 10%. Although etiology of the carcinoma of the gallbladder is still obscure, various factors have been implicated, cholelithiasis being the most frequent. The incidence of GBC worldwide is based on the gender, geography and ethnicity which suggest that both genetic and environmental factors can cause GBC. The major route of spread of gallbladder cancer (GC) is loco-regional rather than distant. It spreads by lymphatic, vascular, neural, intraperitoneal, and intraductal routes. Sonography is usually the most common imaging test to evaluate symptoms of biliary tract disease including suspected GC. With recent advances in imaging modalities like multi-detector computed tomography (CT) scanners, magnetic resonance imaging-positron emission tomography/CT diagnosis of gallbladder cancer has improved. Studies have also targeted molecular and genetic pathways. Treatment options have included extended and radical surgeries and adjuvant chemotherapy. This review article deals in detail with important aspects of carcinoma gallbladder and its manifestations and challenges. Role of various imaging modalities in characterization and accurate staging has been discussed. The loco-regional spread of this aggressive malignancy is dealt explicitly.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.