Evidence map›Paper›PMID 25789137›Full record

ArticleInternational journal of preventive medicine2015

Endothelial Function in Patients with Migraine without Aura during the Interictal Period.

Kiyan Heshmat-Ghahdarijani, Shaghayegh Haghjooy Javanmard, Seyed Ali Sonbolestan, Mohammad Saadatnia, Seyed Ahmad Sonbolestan

Open access · goldAbstract read
In one paragraph

Article in International journal of preventive medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Pathophysiological Bases of Comorbidity in Migraine.Frontiers in human neuroscience · 2021
    Review
  5. Article
  6. Migraine and subclinical atherosclerosis: endothelial dysfunction biomarkers and carotid intima-media thickness: a case-control study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019
    Article
  7. The serum level of inflammatory markers in chronic and episodic migraine: a case-control study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kiyan Heshmat-GhahdarijaniDepartment of Cardiology, Isfahan University of Medical Sciences, Isfahan, Iran.
Shaghayegh Haghjooy JavanmardApplied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Seyed Ali SonbolestanDepartment of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran.
Mohammad SaadatniaDepartment of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran.
Seyed Ahmad SonbolestanDepartment of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran.
Isfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn most of the studies, the association of vascular events is limited to migraine with aura or it is stronger in this group, whereas the link between migraine without aura (MO) and vascular events remained uncertain. Therefore, we decided to evaluate endothelial function by chemical and functional markers of endothelium in MO and compare with normal population.

methodsIn this study, 39 patients and 25 healthy subjects were enrolled and flow-mediated dilatation (FMD), C-reactive protein (CRP), nitrite and nitrate were measured in these two groups.

resultsThe mean of FMD in healthy people was higher than the migraine patients (mean difference - 7.67%; 95% confidence interval [CI] -9.90--5.44). The means of nitrite concentration in migraineurs was significantly lower than healthy subjects (mean difference - 2.0 μmol/L; 95% CI - 3.45--0.54). But the CRP concentrations in both groups were not significantly different (mean difference 0.42 pmol/L; 95% CI - 0.13-0.98).

conclusionsThis study can show the endothelial dysfunction in migraineurs without aura and suggest that MO could also be a risk for cardiovascular disease.

Indexed as

C-reactive proteinendothelial dysfunctionflow-mediated dilatationmigraine without auranitric oxide

Identifiers

PMID25789137
PMCPMC4362278
OpenAlexW1991616452

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.